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Merck
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Key Documents

B3303

Sigma-Aldrich

Buserelin acetate salt

≥90% (HPLC)

Sinónimos:

des-Gly10-[D-Ser[t-Bu]6]-LH-RH ethylamide acetate salt, pGlu-His-Trp-Ser-Tyr-D-Ser(t-Bu)-Leu-Arg-Pro-NHEt acetate salt

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About This Item

Fórmula empírica (notación de Hill):
C60H86N16O13 · C2H4O2
Número de CAS:
68630-75-1
Peso molecular:
1299.48
MDL number:
MFCD00941414
UNSPSC Code:
51111800
NACRES:
NA.32

assay

≥90% (HPLC)

form

powder

UniProt accession no.

P12391

storage temp.

−20°C

InChI

1S/C60H86N16O13.C2H4O2/c1-7-64-57(87)48-15-11-23-76(48)58(88)41(14-10-22-65-59(61)62)69-51(81)42(24-33(2)3)70-56(86)47(31-89-60(4,5)6)75-52(82)43(25-34-16-18-37(78)19-17-34)71-55(85)46(30-77)74-53(83)44(26-35-28-66-39-13-9-8-12-38(35)39)72-54(84)45(27-36-29-63-32-67-36)73-50(80)40-20-21-49(79)68-40;1-2(3)4/h8-9,12-13,16-19,28-29,32-33,40-48,66,77-78H,7,10-11,14-15,20-27,30-31H2,1-6H3,(H,63,67)(H,64,87)(H,68,79)(H,69,81)(H,70,86)(H,71,85)(H,72,84)(H,73,80)(H,74,83)(H,75,82)(H4,61,62,65);1H3,(H,3,4)/t40-,41-,42-,43-,44-,45-,46-,47+,48-;/m0./s1

InChI key

PYMDEDHDQYLBRT-DRIHCAFSSA-N

Gene Information

rat ... Chrnb3(171131)

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Amino Acid Sequence

Glp-His-Trp-Ser-Tyr-Ser-tBu-Leu-Arg-Pro-NHEt

Biochem/physiol Actions

Buserelin is an LH-RH agonist.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

hcodes

H302,H360

Hazard Classifications

Acute Tox. 4 Oral - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Cell and tissue research, 351(3), 521-534 (2012-12-21)
Gonadotropin-releasing hormone (GnRH) analogs are given to women undergoing in vitro fertilization. Case reports describing the development of chronic intestinal pseudo-obstruction and auto-antibodies against GnRH after such treatment suggest a strong association between intestinal dysfunction and GnRH analogs. No experimental
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S Zhao et al.
Gynecologic and obstetric investigation, 49(1), 52-56 (2000-01-12)
Gonadotropin-releasing hormone (GnRH) has been found to be expressed in ovaries of various species and to modulate cell differentiation in ovarian cells. GnRH agonists (GnRHa) are widely used in the stimulation protocols of assisted reproduction. In the present study, the
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C M Kershaw-Young et al.
Reproduction, fertility, and development, 24(8), 1093-1097 (2012-09-07)
Ovulation in camelids is induced by an unidentified protein in the seminal plasma of the male termed 'ovulation-inducing factor'. This protein has been reported to be a 14-kDa protein under reducing conditions, which, when purified from seminal plasma, induces ovulation
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