A9101
Acetylcholine chloride
≥99% (TLC), powder or crystals
Sinónimos:
ACh
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About This Item
Fórmula lineal:
(CH3)3N+CH2CH2OCOCH3Cl-
Número de CAS:
Peso molecular:
181.66
Beilstein:
3571875
Número CE:
Número MDL:
Código UNSPSC:
12352204
ID de la sustancia en PubChem:
NACRES:
NA.32
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Nombre del producto
Acetylcholine chloride, pkg of 150 mg (per vial)
Ensayo
≥99% (TLC)
Nivel de calidad
Formulario
powder or crystals
envase
pkg of 150 mg (per vial)
mp
146-150 °C (lit.)
solubilidad
H2O: soluble
temp. de almacenamiento
room temp
cadena SMILES
[Cl-].CC(=O)OCC[N+](C)(C)C
InChI
1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
Clave InChI
JUGOREOARAHOCO-UHFFFAOYSA-M
Información sobre el gen
human ... CHRM3(1131)
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Descripción general
Acetylcholine is an important neurotransmitter that plays a critical role in multiple neurological systems. Crucial for neurobiology studies, acetylcholine aids researchers in understanding synaptic transmission. In other forms of research, acetylcholine has an effect and influence on tumor neurobiology for cancer R&D, as well as a variety of other cognitive processes.
Aplicación
For use as a substrate to determine acetylcholinesterase activity. Acetylcholine chloride has been used:
- for standard curve preparation in hestrin assay
- in Protein expression, radioactive ligand binding assay and electrophysiological studies of Lymnaea stagnalis acetylcholine binding protein (Ls-AChBPs)
- as a supplement in extracellular solutions for treating the voltage clamped cells in electrophysiology studies
Acciones bioquímicas o fisiológicas
Acetyl choline (ACh) is an essential neurotransmitter in both central and peripheral nervous system. ACh binds to nicotinic acetylcholine receptors (nAChRs) and causes fast excitatory neurotransmission.
Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergic anti-inflammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.
Endogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.
Reconstitución
Reconstituted solution is stable for 2 weeks when stored at 2-8 °C
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
dust mask type N95 (US), Eyeshields, Gloves
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