A0788

3-Aminobenzamide

≥99% (TLC)

• Sinónimos: 3-AB, 3-ABA
• Fórmula lineal: H₂NC₆H₄CONH₂
• Número de CAS: 3544-24-9
• Peso molecular: 136.15
• Número CE: 222-586-9
• Número MDL: MFCD00007989
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24278206
• NACRES: NA.77

Propiedades

• Ensayo: ≥99% (TLC)
• Formulario: powder
• color: white to off-white
• mp: 115-116 °C (lit.)
• solubilidad: ethanol: 50 mg/mL, clear, light yellow; DMSO: soluble; H₂O: soluble (may require gentle heating)
• temp. de almacenamiento: room temp
• cadena SMILES: NC(=O)c1cccc(N)c1
• InChI: 1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10)
• Clave InChI: GSCPDZHWVNUUFI-UHFFFAOYSA-N
• Información sobre el gen: mouse ... Parp1(11545)

Descripción

Aplicación

3-Aminobenzamide has been used as a poly-(ADP-ribose) polymerase (PARP) inhibitor in various experimental studies.

Acciones bioquímicas o fisiológicas

3-Aminobenzamide enhances cell death, unscheduled DNA synthesis and repair replication by interrupting the rejoining of DNA strand breaks induced by both ionizing radiations and several alkylating agents. It has an ability to inhibit the activity of nuclear enzyme poly (ADP-ribose) synthetase (PARS). 3-Aminobenzamide exhibits protective action against myocardial reperfusion injury and local inflammation.

Características y beneficios

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Gloves