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Key Documents

930-05A

Sigma-Aldrich

Human Renal Proximal Tubular Epithelial Cells: HRPTEpC, adult

Sinónimos:

Proximal Tubular Epithelial Cells

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About This Item

UNSPSC Code:
41106514
NACRES:
NA.81

biological source

human kidney

Quality Level

100

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

technique(s)

cell culture | mammalian: suitable

shipped in

dry ice

storage temp.

−196°C

General description

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

Human Renal Proximal Tubular Epithelial Cells (HRPTEpC) provide a useful tool for studying various aspects of pathology and biology of the human renal proximal tubular cells in vitro. HRPTEpC have recently been used in a study of metabolic enzymes responding to energy depletion in renal cells. HRPTEpCs have a pivotal role in kidney function including reabsorbtion of glucose and protein, and also play a part in the glucotoxicity associated with diabetes.

Cell Line Origin

Kidney

Application

Kidney disease, diabetes, glucotoxicity, pathology. kidney function, reabsorbtion of glucose and protein, biology of renal proximal tubular cells in vitro, metabolic enzymes, cell energy usage.

Packaging

First or second passage, >500,000 cells in RenaEpi Basal Medium containing 10% FBS & 10% DMSO.

Components

RenaEpi Basal Medium containing 10% FBS & 10% DMSO

Quality

Each lot was tested for proper morphology, ability to attach and spread on tissue culture ware surface, and proliferate in RenaEpi Growth Medium, Negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi.

Other Notes

Can be cultured at least 6 population doublings

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Fatimah K Khalaf et al.
Journal of the American Heart Association, 9(3), e013933-e013933 (2020-02-06)
Background Recent studies have highlighted a critical role for a group of natriuretic hormones, cardiotonic steroid (CTS), in mediating renal inflammation and fibrosis associated with volume expanded settings, such as chronic kidney disease. Immune cell adhesion is a critical step
Duygu Elif Yilmaz et al.
The Journal of biological chemistry, 298(3), 101589-101589 (2022-01-17)
Current immunosuppressive strategies in organ transplantation rely on calcineurin inhibitors cyclosporine A (CsA) or tacrolimus (Tac). Both drugs are nephrotoxic, but CsA has been associated with greater renal damage than Tac. CsA inhibits calcineurin by forming complexes with cyclophilins, whose

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