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77631

Sigma-Aldrich

(R)-Mevalonic acid 5-pyrophosphate tetralithium salt

≥95% (TLC)

Sinónimos:

(R)-Mevalonic acid 5-diphosphate tetralithium salt, R-MVAPP

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About This Item

Fórmula empírica (notación de Hill):
C6H10Li4O10P2
Número de CAS:
1485654-39-4
Peso molecular:
331.85
MDL number:
MFCD16875407
UNSPSC Code:
12352106
PubChem Substance ID:
329767829
NACRES:
NA.25

assay

≥95% (TLC)

form

powder

optical activity

[α]/D -2.9±0.5°, c = 1 in hydrochloric acid (0.02 M)

storage temp.

−20°C

SMILES string

[Li+].[Li+].[Li+].[Li+].C[C@@](O)(CCOP([O-])(=O)OP([O-])([O-])=O)CC([O-])=O

InChI

1S/C6H14O10P2.4Li/c1-6(9,4-5(7)8)2-3-15-18(13,14)16-17(10,11)12;;;;/h9H,2-4H2,1H3,(H,7,8)(H,13,14)(H2,10,11,12);;;;/q;4*+1/p-4/t6-;;;;/m1..../s1

InChI key

GFIXUUFXTAPBAD-CZNRRTBNSA-J

Categorías relacionadas

Biochem/physiol Actions

Metabolite of the mevalonate pathway, which plays a key role in the biosynthesis of sterols, dolichol, heme and ubiquinone. Of interest for research in the disease areas oncology, autoimmune diseases, artherosclerosis and Alzheimer disease, as well as for inherited deficiencies of mevalonate kinase.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sigma-Aldrich

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Genetic, epidemiologic, and biochemical evidence suggests that predisposition to Alzheimer's disease (AD) may arise from altered cholesterol metabolism, although the molecular pathways that may link cholesterol to AD phenotypes are only partially understood. Here, we perform a phenotypic screen for

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