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D5879

Sigma-Aldrich

Dimetilsulfóxido

ReagentPlus®, ≥99.5%

Sinónimos:

DMSO

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About This Item

Fórmula lineal:
(CH3)2SO
Número de CAS:
67-68-5
Peso molecular:
78.13
Beilstein:
506008
Número CE:
200-664-3
Número MDL:
MFCD00002089
Código UNSPSC:
12191502
ID de la sustancia en PubChem:
329798814
NACRES:
NA.21
Ensayo:
≥99.5%
técnicas:
immunoblotting: suitable
bp:
189 °C (lit.)
presión de vapor:
0.42 mmHg ( 20 °C)
En este momento no podemos mostrarle ni los precios ni la disponibilidad

densidad de vapor

2.7 (vs air)

Nivel de calidad

200

presión de vapor

0.42 mmHg ( 20 °C)

Línea del producto

ReagentPlus®

Ensayo

≥99.5%

Formulario

liquid

temp. de autoignición

573 °F

lim. expl.

42 %, 63 °F

técnicas

immunoblotting: suitable

impurezas

≤0.1% water (Karl Fischer)

índice de refracción

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubilidad

H2O: soluble(lit.)
acetone: soluble(lit.)
benzene: soluble(lit.)
chloroform: soluble(lit.)
ethanol: soluble(lit.)

densidad

1.10 g/mL (lit.)

cadena SMILES

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

Clave InChI

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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Descripción general

El dimetilsulfóxido es una molécula anfipática, soluble tanto en disolventes acuosos como en disolventes orgánicos.[1] Se utiliza normalmente como disolvente aprótico[2] y también como reactivo en síntesis orgánicas.[3]

Aplicación

El DMSO se ha utilizado como medio para preparar un reactivo quimioluminiscente que pueda ser un sustituto para los kits de quimioluminiscencia mejorada comercializados para la técnica de inmunotransferencia.[4]

Acciones bioquímicas o fisiológicas

El DMSO es una sustancia muy popular que puede utilizarse como un disolvente industrial para compuestos químicos orgánicos e inorgánicos. También se utiliza como protector durante la conservación en frío de las células vivas.[5][6] Es útil también para la oxidación de tioles y disulfuros a ácidos sulfónicos.[7]

Envase

Nota: D5879-1L en botella de vidrio /D5879-1L-D en botella de polietileno.

Precaución

Fácilmente superenfriado, vuelve a fundir lentamente a temperatura ambiente. Producto solidificado que puede volver a licuarse por calentamiento a temperatura ambiente sin detrimento del producto.

Otras notas

Si desea información sobre la miscibilidad del dimetilsulfóxido, visite el siguiente enlace:
Tabla de miscibilidad/inmiscibilidad del dimetilsulfóxido

Información legal

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

188.6 °F - closed cup

Punto de inflamabilidad (°C)

87 °C - closed cup

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Certificados de análisis (COA)

Lot/Batch Number
SHBS5696
SHBS4012
SHBR5702
SHBR8760
SHBR7065

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Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Lowe, O.G
The Journal of Organic Chemistry, 41 (1976)
Levent Keskintepe et al.
Journal of assisted reproduction and genetics, 26(11-12), 629-635 (2009-12-08)
Cryopreservation of blastocysts, especially those subjected to the trauma due to blastomere biopsy for the purposes of pre-implantation genetic screening (PGS), requires significant optimization. Laboratory and clinical outcomes were compared to determine the effect of two different cryopreservation techniques on
Activated dimethyl sulfoxide: useful reagents for synthesis.
Mancuso AJ and Swern D.
Synthesis, 1981(03), 165-185 (1981)
M Bouquet et al.
Molecular reproduction and development, 40(1), 110-115 (1995-01-01)
In a previous study, we have shown that the cryopreservation of mouse oocytes caused increases in the rates of degeneration and of digynic polyploid embryos, while the fertility of frozen-thawed oocytes was decreased. In this study, we have attempted to
Sun-A Ock et al.
Cell transplantation, 20(8), 1231-1239 (2011-02-08)
Dimethyl sulfoxide (DMSO), a commonly used cryoprotectant in cryopreservation procedures, is detrimental to viability of cells. In this view point, a comparative study was carried out to evaluate the effect of DMSO on porcine mesenchymal stem cells (pMSCs). We compared
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Questions

1–7 of 7 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. Is the DMSO (Dimethyl Sulfoxide) still considered usable if it was received in a frozen or solid form?

    1 answer

    1. Yes, DMSO (Dimethyl Sulfoxide) is still considered usable even if it was received in a frozen or solid form. The solidified DMSO can be easily re-liquefied by warming it to room temperature.

      Helpful?

  4. The Dimethyl sulfoxide, Product D5879,  I ordered arrived as a solid. Is the product still acceptable?

    1 answer

    1. Sigma-Aldrich ships many products, including DMSO, at ambient temperature. As a result product D5879 might arrive as a solid depending on the weather conditions during shipment. The melting point of DMSO is 16-19°C. Therefore, if the solid is allowed to warm to room temperature, it will melt without any impact on the quality of the product.

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  5. What is the molarity of Product D5879, Dimethyl sulfoxide?

    1 answer

    1. Pure solvents do not technically have a molarity (defined as moles of solute per liter of solution), since there is no solute distinct from the pure material. However, an effective molar concentration of 14.1M can be determined for this product, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

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  6. My application requires a dry solvent. How can I remove water that is present in Dimethyl sulfoxide, Product D5879?

    1 answer

    1. This product has a water content specification of not more than 0.1%, which may be low enough for your application. Other DMSO products may have more water present. Molecular sieves are typically zeolite compounds that strongly adsorb water and have carefully controlled pore sizes. If you would like, dried sieves may be placed into the bulk solvent container (about 5%-10% by volume) to remove most water.  Sigma-Aldrich offers 4 Å molecular sieves (e.g. product 334308), which would be effective in removing residual water from DMSO.

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  7. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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