32211

Cloroformo

puriss. p.a., reag. ISO, reag. Ph. Eur., 99.0-99.4% (GC)

• Sinónimos: Triclorometano, Tricloruro de metilidino
• Fórmula empírica (notación de Hill): CHCl₃
• Número de CAS: 67-66-3
• Peso molecular: 119.38
• Beilstein/REAXYS Number: 1731042
• EC Number: 200-663-8
• MDL number: MFCD00000826
• UNSPSC Code: 12191502
• PubChem Substance ID: 329754102
• NACRES: NA.04

Propiedades

• agency: USP/NF; reag. ISO; reag. Ph. Eur.
• Quality Level: 200
• vapor density: 4.1 (vs air)
• vapor pressure: 160 mmHg ( 20 °C)
• grade: puriss. p.a.
• assay: 99.0-99.4% (GC)
• form: liquid
• contains: ~1% ethanol as stabilizer
• technique(s): RNA extraction: suitable
• impurities: ≤0.00001% free chlorine (Cl); ≤0.00005% free acid (as HCl); ≤0.0005% non-volatile matter; ≤0.005% aldehydes and ketones (as CH₃COCH₃); ≤0.005% carbonyl compounds (as CO); ≤0.01% tetrachloroethene (GC); ≤0.01% tetrachloromethane (GC); ≤0.01% trichloroethene (GC); ≤0.01% water (Karl Fischer); ≤0.03% dichloromethane (GC); 0.6-1.0% ethanol (GC)
• refractive index: n20/D 1.445 (lit.)
• bp: 60.5-61.5 °C (lit.)
• mp: −63 °C (lit.)
• density: 1.476-1.483 g/mL at 20 °C; 1.492 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤1 mg/kg
• cation traces: Al: ≤0.5 mg/kg; B: ≤0.02 mg/kg; Ba: ≤0.1 mg/kg; Ca: ≤0.5 mg/kg; Cd: ≤0.05 mg/kg; Co: ≤0.02 mg/kg; Cr: ≤0.02 mg/kg; Cu: ≤0.02 mg/kg; Fe: ≤0.1 mg/kg; Mg: ≤0.1 mg/kg; Mn: ≤0.02 mg/kg; Ni: ≤0.02 mg/kg; Pb: ≤0.05 mg/kg; Sn: ≤0.1 mg/kg; Zn: ≤0.1 mg/kg
• SMILES string: ClC(Cl)Cl
• suitability: complies for appearance; complies for reaction against H₂SO₄; complies for suitability of determ. w. dithizone
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• InChI key: HEDRZPFGACZZDS-UHFFFAOYSA-N

Descripción

General description

Chloroform, a halogenated hydrocarbon, is widely employed as a solvent. Its photochemical degradation has been investigated in the presence of TiO₂ aqueous suspensions (wavelength range of 310-380nm).

Application

Chloroform may be employed as a solvent for the following studies:

• Extraction of RNA from plant cells.
• Preparation of dioleoylphosphatidylcholine (DOPC) solution.
• Dissolution of 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC).

It may be employed in a rapid quantitative method for the release of periplasmic proteins from bacterial strains.

Chloroform may be used as a solvent to enhance the enantioselectivity of secondary alcohols formed by the borohydride reduction of carbonyl compounds in the presence of optically active ketoiminatocobalt complexes.

Other Notes

For information on chloroform miscibility, please visit the following link:
Chloroform Miscibility/Immiscibility Table

The article number 32211-4X2.5L will be discontinued. Please order the single bottle 32211-2.5L which is physically identical with the same exact specifications.
The article number 32211-4X2.5L-M will be discontinued. Please order the single bottle 32211-2.5L-M which is physically identical with the same exact specifications.
The article number 32211-6X1L will be discontinued. Please order the single bottle 32211-1L which is physically identical with the same exact specifications.
The article number 32211-6X1L-M will be discontinued. Please order the single bottle 32211-1L-M which is physically identical with the same exact specifications.

Información de seguridad

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372
• pcodes: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: does not flash
• flash_point_c: does not flash