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Y0001462

Acetylsulfadiazine

European Pharmacopoeia (EP) Reference Standard

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About This Item

Fórmula empírica (notación de Hill):
C12H12N4O3S
Número de CAS:
Peso molecular:
292.31
Código UNSPSC:
41116107
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

sulfadiazine

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

[S](=O)(=O)(Nc2ncccn2)c1ccc(cc1)NC(=O)C

InChI

1S/C12H12N4O3S/c1-9(17)15-10-3-5-11(6-4-10)20(18,19)16-12-13-7-2-8-14-12/h2-8H,1H3,(H,15,17)(H,13,14,16)

Clave InChI

NJIZUWGMNCUKGU-UHFFFAOYSA-N

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Acetylsulfadiazine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

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D Westerlund et al.
Journal of pharmaceutical sciences, 71(10), 1142-1145 (1982-10-01)
Sulfadiazine and N4-acetylsulfadiazine were determined in biological fluids by the direct injection (plasma after protein precipitation and urine after dilution 100 times) of 20 microliters on a silica gel column. The mobile phase was an aqueous citrate buffer (pH 4.0)
The case: 69 year old man with sand in the urine. N-acetylsulfadiazine crystals.
A K Schuler et al.
Kidney international, 72(6), 769-770 (2007-09-07)
T Bergan et al.
Chemotherapy, 32(6), 478-485 (1986-01-01)
The study was aimed at analyzing the pharmacokinetics of sulphadiazine (SDZ) and trimethoprim (TMP) in geriatric patients and was carried out in two stages. The first stage compared 11 geriatric patients (68-89 years old) and 9 healthy volunteers (21-34 years
Sulfadiazine/N4-acetylsulfadiazine crystalluria in a patient with the acquired immune deficiency syndrome (AIDS)
J L Potter et al.
Clinica chimica acta; international journal of clinical chemistry, 230(2), 221-224 (1994-10-31)
Turner's syndrome with anorexia nervosa.
T Ohzeki et al.
The American journal of medicine, 84(4), 792-793 (1988-04-01)

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