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Merck
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Key Documents

Y0001104

Picosulfate for system suitability

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

Sodium picosulfate

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About This Item

Fórmula empírica (notación de Hill):
C18H13NNa2O8S2
Número de CAS:
10040-45-6
Peso molecular:
481.41
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

sodium picosulfate

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C18H15NO8S2.2Na/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25;;/h1-12,18H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2

InChI key

GOZDTZWAMGHLDY-UHFFFAOYSA-L

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Picosulfate for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Naoki Hosoe et al.
Journal of gastroenterology and hepatology, 27(10), 1617-1622 (2012-06-01)
In Japan, patient acceptance of bowel preparation methods before colonoscopy remains unknown. This study was conducted to evaluate the patient acceptance of sodium phosphate (NaP) tablets and polyethylene glycol solution (PEG) with sodium picosulfate. One hundred patients were randomized into
Annie O O Chan
Hong Kong medical journal = Xianggang yi xue za zhi, 18(5), 388-394 (2012-09-29)
OBJECTIVES. Although Picolax (sodium picosulphate and magnesium citrate) has been widely documented for use in bowel preparation, there is limited literature on its efficacy in the treatment of constipation. Refractory constipation is a more difficult situation with limited treatment options
Drug eruption due to sodium picosulfate.
Asuka Ishikawa et al.
European journal of dermatology : EJD, 22(3), 410-411 (2012-03-13)
Douglas K Rex et al.
Gastrointestinal endoscopy, 78(1), 132-141 (2013-04-10)
New bowel cleansers for colonoscopy that lead to improved efficacy, safety, and tolerability are needed. This study evaluated a nonphosphate, dual-action, low-volume, orange-flavored preparation containing sodium picosulfate and magnesium citrate (P/MC). Multicenter, assessor-blinded, randomized, noninferiority study. University hospitals, academic medical
Jennifer A Flemming et al.
Gastrointestinal endoscopy, 75(3), 537-544 (2011-12-24)
Picosulfate, magnesium oxide, and citric acid solution is a small-volume agent for colon cleansing before colonoscopy that is extremely well tolerated by patients, safe, and efficacious. Studies of other cleansing agents have suggested that split-dose regimens may further enhance efficacy.
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