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Y0001099

Valaciclovir impurity G

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

4-(Dimethylamino)pyridine, N,N-Dimethylpyridin-4-amine, DMAP

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About This Item

Fórmula empírica (notación de Hill):
C7H10N2
Número de CAS:
1122-58-3
Peso molecular:
122.17
Beilstein/REAXYS Number:
110354
MDL number:
MFCD00006418
UNSPSC Code:
41116107
PubChem Substance ID:
329831263
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

valacyclovir

manufacturer/tradename

EDQM

mp

108-110 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CN(C)c1ccncc1

InChI

1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3

InChI key

VHYFNPMBLIVWCW-UHFFFAOYSA-N

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General description

4-(Dimethylamino)pyridine (DMAP) is an excellent catalyst for acylation of hindered alcohols and in chemical transformations. It is highly nucleophilic in nature.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

A highly efficient catalyst for acylation reactions

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1

target_organs

Nervous system

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

255.2 °F

flash_point_c

124 °C

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Certificados de análisis (COA)

Lot/Batch Number

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Configurationally Stable Biaryl Analogues of 4-(Dimethylamino) pyridine: A Novel Class of Chiral Nucleophilic Catalysts.
Spivey, Alan C., et al.
The Journal of Organic Chemistry, 64.26, 9430-9443 (1999)
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The objective of this study is to design a drug delivery system (DDS) for the in vivo promotion of macrophage recruitment. As the drug, a water-insoluble agonist of sphingosine-1-phosphate type 1 receptor (SEW2871) was selected. SEW2871 (SEW) was water-solubilized by
Aniruddha Roy et al.
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Taxanes are a class of anticancer agents with a broad spectrum and have been widely used to treat a variety of cancer. However, its long-term use has been hampered by accumulating toxicity and development of drug resistance. The most extensively
André R Fajardo et al.
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Despite a growing interest in amphiphilic polysaccharide-based diblock copolymers as functional polymeric drug delivery nanosystems, biologically relevant sulfated glycosaminoglycan systems were not yet investigated. Here, we report the synthesis and the self-assembly properties in water of chondroitin sulfate-b-poly(lactic acid) (CS-b-PLA(n)).
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