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Y0000510

Desogestrel

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

13-Ethyl-11-methylene-18,19-dinor-17α-4-pregnen-20-yn-17-ol

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About This Item

Fórmula empírica (notación de Hill):
C22H30O
Número de CAS:
54024-22-5
Peso molecular:
310.47
Número MDL:
MFCD00869346
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329830993
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

desogestrel

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

temp. de almacenamiento

2-8°C

cadena SMILES

CC[C@]12CC(=C)[C@H]3[C@@H](CCC4=CCCC[C@H]34)[C@@H]1CC[C@@]2(O)C#C

InChI

1S/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1

Clave InChI

RPLCPCMSCLEKRS-BPIQYHPVSA-N

Información sobre el gen

human ... PGR(5241)

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Desogestrel for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Y0000509

Desogestrel, European Pharmacopoeia (EP) Reference Standard

1173268

Etonogestrel, United States Pharmacopeia (USP) Reference Standard

1173235

Desogestrel, United States Pharmacopeia (USP) Reference Standard

1173257

Desogestrel Related Compound B, United States Pharmacopeia (USP) Reference Standard

1173246

Desogestrel Related Compound A, United States Pharmacopeia (USP) Reference Standard

1173279

Desogestrel Related Compound D, United States Pharmacopeia (USP) Reference Standard

PHR1830

Desogestrel, Pharmaceutical Secondary Standard; Certified Reference Material

BP816

Etonogestrel, British Pharmacopoeia (BP) Reference Standard

BP817

Desogestrel impurity E, British Pharmacopoeia (BP) Reference Standard

Pictogramas

Health hazardEnvironment
GHS08,GHS09

Palabra de señalización

Danger

Frases de peligro

H360FD,H410

Clasificaciones de peligro

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B

Código de clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Clase de riesgo para el agua (WGK)

WGK 3

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Certificados de análisis (COA)

Lot/Batch Number

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K Fotherby
Contraception, 51(1), 3-12 (1995-01-01)
The clinical experience with a combined oral contraceptive (COC) containing 150 micrograms desogestrel and 30 micrograms ethinylestradiol is reviewed. Fourteen clinical trials have been reported involving over 44,000 women for more than 190,000 cycles. None of the 17 pregnancies which
H D McClamrock et al.
American journal of obstetrics and gynecology, 168(3 Pt 2), 1021-1028 (1993-03-01)
A synthetic form of desogestrel, a gonane progestin, was developed because desogestrel's enhanced selectivity eliminates adverse, androgen-dependent, metabolic effects at contraceptive doses. Desogestrel is rapidly and completely metabolized in the liver and gut wall to 3-keto-desogestrel, which is the active
D Shoupe
American journal of obstetrics and gynecology, 168(3 Pt 2), 1041-1047 (1993-03-01)
Associated with progesterone and the synthetic progestins used in oral contraceptives is a dose-dependent impairment of carbohydrate metabolism. It is well known that in the general population hyperinsulinemia and alterations in glucose metabolism are significant risk factors for the development
Carolina Scala et al.
Expert opinion on drug safety, 12(3), 433-444 (2013-04-09)
Desogestrel (DSG) is a third-generation progestin. It is commonly used in various formulations for hormonal contraception including combinations with ethinyl estradiol (EE), progestin-only pill and subdermal implants. DSG is also used in menopausal patients for hormone replacement therapy (HRT). The
D F Archer
American journal of obstetrics and gynecology, 170(5 Pt 2), 1550-1555 (1994-05-01)
Desogestrel is a highly selective gonane progestin. A monophasic formulation containing 150 micrograms of desogestrel and 30 micrograms of ethinyl estradiol has recently been approved as an oral contraceptive (OC) in the United States. Although desogestrel-containing formulations are new to
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