PHR2497

1-Methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinónimos: 1,2,3,4-Tetrahydroharmane-3-carboxylic acid, 1-Methyl-1,2,3,4-Tetrahydropyrido[3,4-b]indole-3-carboxylic acid, 1-Methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid, NSC 26225
• Fórmula empírica (notación de Hill): C₁₃H₁₄N₂O₂
• Número de CAS: 5470-37-1
• Peso molecular: 230.26
• MDL number: MFCD00022199
• UNSPSC Code: 41116107
• NACRES: NA.24

Propiedades

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1604337
• API family: tryptophan
• form: solid
• packaging: pkg of 50 mg
• application(s): pharmaceutical small molecule
• storage temp.: -10 to -25°C
• SMILES string: CC1NC(Cc2c1[nH]c3ccccc23)C(O)=O
• InChI: 1S/C13H14N2O2/c1-7-12-9(6-11(14-7)13(16)17)8-4-2-3-5-10(8)15-12/h2-5,7,11,14-15H,6H2,1H3,(H,16,17)
• InChI key: ZUPHXNBLQCSEIA-UHFFFAOYSA-N

Descripción

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Application

Reactant involved in synthesis of molecules for biological studies including:

• Cytotoxicity and insecticidal activities of harmine derivatives
• Isoquinolines, β-carbolines, and 3-deazapurines via oxidative decarboxylation
• Cytotoxic evaluation of 1,3-di- and 1,3,9-trisubstituted β-carbolines

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Información de seguridad

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable