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Merck

PHR2438

Supelco

Chloroquine Related Compound A

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

4,7-Dichloroquinoline

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About This Item

Fórmula empírica (notación de Hill):
C9H5Cl2N
Número de CAS:
Peso molecular:
198.05
Beilstein/REAXYS Number:
125359
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

biological source

synthetic

Quality Level

grade

certified reference material
pharmaceutical secondary standard

agency

BP
EP
USP
traceable to USP 1118328

vapor pressure

0.0000811 kPa ( 25 °C)

API family

chloroquine

form

crystalline

packaging

pkg of 50 mg

color

white to brown

pH

3.86 (24.9 °C)

bp

298.4 °F (148°C)

mp

81-83 °C (lit.)

solubility

water: slightly soluble 0.037 g/L at 25 °C
ethanol: freely soluble
ether: freely soluble

density

1.31 g/cm3 at 20 °C (971.4 hPa)

application(s)

pharmaceutical

storage temp.

2-30°C

SMILES string

Clc1ccc2c(Cl)ccnc2c1

InChI

1S/C9H5Cl2N/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H

Inchi Key

HXEWMTXDBOQQKO-UHFFFAOYSA-N

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General description

Chloroquine Related Compound A is an impurity of chloroquine, a 9-aminoquinoline drug that effectively inhibits viral infections in humans.
Chloroquine Related Compound A is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

Application

Chloroquine Related Compound A can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.
Chloroquine Related Compound A can be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC4608 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation markEnvironment

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Warning

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificados de análisis (COA)

Lot/Batch Number

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Visite la Librería de documentos

Chloroquine Phosphate USP Monograph
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 959-959 (2020)
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Vincent MJ, et al.
Virology Journal, 2(1), 1-10 (2005)

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