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Merck

P5338

Sigma-Aldrich

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt

Powder

Sinónimos:

5,6-Diphenyl-3-(2-pyridyl)-1,2,4-triazine-4′,4″-disulfonic acid sodium salt, PDT disulfonate

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About This Item

Fórmula empírica (notación de Hill):
C20H13N4NaO6S2
Número de CAS:
Peso molecular:
492.46
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

Nombre del producto

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt, BioXtra

product line

BioXtra

Quality Level

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

≥300 °C

anion traces

chloride (Cl-): ≤0.1%

cation traces

Al: ≤0.001%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.001%
Pb: ≤0.001%
Zn: ≤0.0005%

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].OS(=O)(=O)c1ccc(cc1)-c2nnc(nc2-c3ccc(cc3)S([O-])(=O)=O)-c4ccccn4

InChI

1S/C20H14N4O6S2.Na/c25-31(26,27)15-8-4-13(5-9-15)18-19(14-6-10-16(11-7-14)32(28,29)30)23-24-20(22-18)17-3-1-2-12-21-17;/h1-12H,(H,25,26,27)(H,28,29,30);/q;+1/p-1

InChI key

ZGVNYCXXBQPDPQ-UHFFFAOYSA-M

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General description

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt is also known as ferrozine.

Application

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4′,4′′-disulfonic acid sodium salt (ABTS) has been used in the ferene-s assay for the accurate determination of intracellular iron from iron oxide nanoparticles.
It has also been used in ABTS radical scavenging assay to determine the antioxidant activity of honey samples.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Wance J J Firdaus et al.
The FEBS journal, 273(13), 3076-3093 (2006-07-05)
We recently reported that the transient expression of polyglutamine tracts of various size in exon 1 of the huntingtin polypeptide (httEx1) generated abnormally high levels of intracellular reactive oxygen species that directly contributed to cell death. Here, we compared the
Ilkay Erdogan Orhan et al.
Natural product communications, 6(3), 375-378 (2011-04-13)
Ficus carica var. domestica Tsch. & Rav. (common fig) is widely grown in Turkey and exported for its edible fruits. In this study, the n-hexane, chloroform, acetone, methanol, n-butanol, and water extracts of the leaves of F. carica var. domestica
Bruno Alies et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(4), 1161-1167 (2011-12-23)
The association constant of ferrozine (5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine-4,4''-disulfonic acid) with Cu(I) to form the chromophoric [Cu(I)(Fz)(2)](3-) complex was determined by UV/Vis titration experiments in Hepes buffer (0.1 M, pH 7.4). An association constant close to 10(12) M(-2), which is significantly weaker than
Jung Hoon Kang
Toxicology letters, 188(1), 20-25 (2009-05-13)
Salsolinol is an endogenous neurotoxin, known to be involved in the pathogenesis of neurodegenerative disorders. In this present study, we have attempted to characterize the oxidative damage of DNA induced by the reaction of salsolinol with ferritin. When DNA was
Dong-Ha Nam et al.
Aquatic toxicology (Amsterdam, Netherlands), 99(3), 351-359 (2010-06-15)
Brevetoxins are persistent, bioaccumulative, lipophilic polyether neurotoxins synthesized by Karenia brevis, a harmful algal bloom (HAB) dinoflagellate. Although some marine organisms accumulate potentially harmful levels of brevetoxins, little is known about neurotoxic effects in wild populations. Here, tissue (i.e., liver

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