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M8054

Sigma-Aldrich

Manganese(II) chloride tetrahydrate

meets USP testing specifications

Sinónimos:

Manganese chloride hydrate, Manganese chloride tetrahydrate, MnCl2.4H2O

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About This Item

Fórmula lineal:
MnCl2 · 4H2O
Número de CAS:
13446-34-9
Peso molecular:
197.91
EC Number:
231-869-6
MDL number:
MFCD00149792
UNSPSC Code:
12352302
PubChem Substance ID:
24897219
NACRES:
NA.21

agency

USP/NF
meets USP testing specifications

Quality Level

300

assay

98.0-101.0% dry basis

form

flakes

mp

58 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]

InChI

1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2

InChI key

CNFDGXZLMLFIJV-UHFFFAOYSA-L

Categorías relacionadas

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Brain

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 2

flash_point_f

does not flash

flash_point_c

does not flash

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000373697
0000373701
0000367188
0000367189
0000366194

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Hiroko Nobuta et al.
Cell stem cell, 25(4), 531-541 (2019-10-05)
Pelizaeus-Merzbacher disease (PMD) is an X-linked leukodystrophy caused by mutations in Proteolipid Protein 1 (PLP1), encoding a major myelin protein, resulting in profound developmental delay and early lethality. Previous work showed involvement of unfolded protein response (UPR) and endoplasmic reticulum
Lisha Luo et al.
NMR in biomedicine, 25(12), 1360-1368 (2012-05-11)
The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Geoffrey J Topping et al.
Medical physics, 40(4), 042502-042502 (2013-04-06)
Manganese(II) is employed as a contrast agent with magnetic resonance imaging (MRI) for study of neuronal activation in rats and mice. However, at the concentrations required for MRI, Mn may induce pharmacological or toxic effects. Positron emission tomography (PET) imaging
Jerome A Roth et al.
Neurotoxicology, 35, 121-128 (2013-01-15)
Chronic exposure to Mn results in the development of a neurological disorder known as manganism characterized by neurological deficits resembling that seen in Parkinsonism. Although dopaminergic neurons within the nigrostriatal pathway appear intact, Mn-induced irregularities in DA transmission have been
Tameshwar Ganesh et al.
Journal of magnetic resonance imaging : JMRI, 41(3), 806-813 (2014-03-05)
To investigate the potential of manganese (Mn)-enhanced MRI for sensitive detection and delineation of tumors that demonstrate little enhancement on Gd-DTPA. Eighteen nude rats bearing 1 to 2 cm in diameter orthotopic breast tumors (ZR75 and LM2) were imaged on
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