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C0470000

Carbocisteine

European Pharmacopoeia (EP) Reference Standard

Sinónimos:

S-Carboxymethyl-L-cysteine, 3-carboxymethylthio-L-alanine

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About This Item

Fórmula empírica (notación de Hill):
C5H9NO4S
Número de CAS:
638-23-3
Peso molecular:
179.19
Beilstein:
1725012
Número MDL:
MFCD00002614
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329774796
NACRES:
NA.24

grado

pharmaceutical primary standard

familia API

carbocisteine

fabricante / nombre comercial

EDQM

aplicaciones

pharmaceutical (small molecule)

Formato

neat

cadena SMILES

N[C@@H](CSCC(O)=O)C(O)=O

InChI

1S/C5H9NO4S/c6-3(5(9)10)1-11-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1

Clave InChI

GBFLZEXEOZUWRN-VKHMYHEASA-N

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Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Carbocisteine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Envase

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Otras notas

Sales restrictions may apply.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number

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Boontarika Boonyapiwat et al.
The Journal of pharmacy and pharmacology, 63(4), 558-564 (2011-03-16)
The aim of this investigation was to provide in-vitro enzyme kinetic data to support the hypothesis that the in-vivo heterozygous dominant phenotype for phenylalanine monooxygenase (hPAH) was responsible for the S-oxidation polymorphism in the metabolism of S-carboxymethyl-l-cysteine reported in humans.
Matthew Thomas Hardison et al.
Frontiers in bioscience (Elite edition), 4, 2402-2409 (2012-06-02)
Several chronic lung diseases have been linked to cigarette smoking (Chronic Obstructive Pulmonary Disease (COPD), and cancer are associated with increased tobacco use). We recently described a collagen fragment, proline-glycine-proline (PGP), chemotactic for neutrophils, that appears to play a role
Masayuki Hanaoka et al.
Chest, 139(5), 1101-1108 (2010-09-18)
Chronic inflammation, imbalance of proteolytic and antiproteolytic activities, oxidative stress, and apoptosis of lung structural cells contribute to the pathogenesis of COPD. There is increasing evidence that carboxymethylcysteine (also known as carbocisteine) (CMC), which is commonly used for its mucoactive
[Notes on syrups and dry syrups of ambroxol hydrochloride and L-carbocysteine].
Naoto Watanabe et al.
Arerugi = [Allergy], 61(5), 659-661 (2012-08-29)
Pauline Mallet et al.
PloS one, 6(7), e22792-e22792 (2011-08-06)
To report pediatric cases of paradoxical respiratory adverse drug reactions (ADRs) after exposure to oral mucolytic drugs (carbocysteine, acetylcysteine) that led to the withdrawal of licenses for these drugs for infants in France and then Italy. The study followed the
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