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Merck

BP653

Famotidine

British Pharmacopoeia (BP) Reference Standard

Sinónimos:

N′-(Aminosulfonyl)-3-([2-(diaminomethyleneamino)-4-thiazolyl]methylthio)propanamidine

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About This Item

Fórmula empírica (notación de Hill):
C8H15N7O2S3
Número de CAS:
Peso molecular:
337.45
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

agency

BP

API family

famotidine

form

solid

shelf life

limited shelf life, expiry date on the label

packaging

pkg of 100 mg

manufacturer/tradename

BP

storage condition

OK to freeze

color

white

mp

162-165 °C

solubility

water: insoluble

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

shipped in

ambient

storage temp.

2-8°C

SMILES string

N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1

InChI

1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)

InChI key

XUFQPHANEAPEMJ-UHFFFAOYSA-N

Gene Information

human ... HRH2(3274)

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General description

Famotidine is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Famotidine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Famotidine Tablets
  • Biochem/physiol Actions

    H2 histamine receptor antagonist; anti-ulcer agent

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    related product

    Referencia del producto
    Descripción
    Precios

    Storage Class

    11 - Combustible Solids

    wgk_germany

    WGK 2

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable


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    Certificados de análisis (COA)

    Lot/Batch Number

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    Visite la Librería de documentos

    Famotidine
    British Pharmacopeia
    British Pharmacopoeia, 29(1-2), 247-254 (2020)
    Determination of famotidine in acid reduction tablets by HPTLC and videodensitometry of fluorescence quenched zones
    Campbell AN and Sherma J
    Journal of Liquid Chromatography and Related Technologies, 26(16), 2719-2727 (2003)
    Determination of cimetidine, famotidine, and ranitidine hydrochloride in the presence of their sulfoxide derivatives in pure and dosage forms by high-performance thin-layer chromatography and scanning densitometry
    Kelani KM, et al.
    Journal of AOAC (Association of Official Analytical Chemists) International, 85(5), 1015-1020 (2002)
    Stability indicating method for famotidine in pharmaceuticals using porous graphitic carbon column
    Helali N and Monser L
    Journal of Separation Science, 31(2) (2008)
    Development and validation of chromatographic methods for simultaneous determination of ibuprofen and famotidine in presence of related substances in pharmaceutical formulations
    Elzanfaly ES, et al.
    Acta Chimica Slovenica, 62(1) (2014)

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