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Merck

B3420

Sigma-Aldrich

Benzoato de sodio

BioXtra, ≥99.5%

Sinónimos:

Ácido benzoico sodium salt

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About This Item

Fórmula lineal:
C6H5COONa
Número de CAS:
Peso molecular:
144.10
Beilstein/REAXYS Number:
3572467
EC Number:
MDL number:
UNSPSC Code:
12352107
eCl@ss:
39024301
PubChem Substance ID:
NACRES:
NA.25

product line

BioXtra

Quality Level

assay

≥99.5%

form

powder

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

mp

>300 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.10%
Mg: ≤0.005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

[Na+].[O-]C(=O)c1ccccc1

InChI

1S/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1

InChI key

WXMKPNITSTVMEF-UHFFFAOYSA-M

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General description

Sodium benzoate is a safe food preservative and has antimicrobial functionality. It has a molecular weight of 114.11 Da. Sodium benzoate is used in bakery products, juice and cheese. In the liver, it is conjugated to glycine and is eliminated as hippuric acid from the urine.

Application

Sodium benzoate has been used to test its effect on phencyclidine (PCP) induced locomotor activity in mice.

Biochem/physiol Actions

Sodium benzoate also has pharmaceutical applications and is component of syrup and transparent tablet. High levels of sodium benzoate may trigger histamine release and also induce cell damage. It is recommended for the treatment of urea cycle disorders. However, high levels of sodium benzoate may contribute to glycine deficiency and may impose neuromodulatory effects.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Modulating NMDA receptor function with D-amino acid oxidase inhibitors: understanding functional activity in PCP-treated mouse model
Sershen H, et al.
Neurochemical Research, 41(1-2), 398-408 (2016)
Benzoate and sorbate salts: a systematic review of the potential hazards of these invaluable preservatives and the expanding spectrum of clinical uses for sodium benzoate
Piper JD and Piper PW
Comprehensive Reviews in Food Science and Food Safety, 16(5), 868-880 (2017)
An Overview on the Effects of Sodium Benzoate as a Preservative in Food Products
Shahmohammadi M, et al.
Biotechnology and Health Sciences, 3(3), 7-11 (2016)
Matteo Gabba et al.
Biophysical journal, 118(2), 422-434 (2019-12-18)
We present a fluorescence-based approach for determination of the permeability of small molecules across the membranes of lipid vesicles and living cells. With properly designed experiments, the method allows us to assess the membrane physical properties both in vitro and in vivo.
Yue Mu et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 83(1), 130-135 (2011-09-06)
The toxicity of sodium benzoate to trypsin was investigated by fluorescence spectroscopy, synchronous fluorescence spectroscopy, UV-visible absorption spectroscopy and circular dichroism (CD) spectroscopy under mimic physiological conditions. Sodium benzoate could unfold trypsin by decreasing the β-sheet structure, which leads to

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