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A5144

Sigma-Aldrich

8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate

≥95% purity (perchloric acid titration), for fluorescence, powder

Sinónimos:

1,8-ANS magnesium salt, ANSA magnesium salt, Magnesium 8-anilino-1-naphthalenesulfonate hydrate, N-Phenyl peri acid magnesium salt

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About This Item

Fórmula empírica (notación de Hill):
C16H12Mg0.5NO3S · xH2O
Número de CAS:
18108-68-4
Peso molecular:
310.49 (anhydrous basis)
Beilstein/REAXYS Number:
4834623
EC Number:
242-004-7
MDL number:
MFCD16661224
UNSPSC Code:
12171500
PubChem Substance ID:
329770870
NACRES:
NA.47

product name

8-Anilino-1-naphthalenesulfonic acid hemimagnesium salt hydrate, for fluorescence, ≥95% (TLC)

grade

for fluorescence

Quality Level

200

assay

≥95% (TLC)

form

powder

color

faint green to green

solubility

H2O: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

O.[Mg++].[O-]S(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12.[O-]S(=O)(=O)c4cccc5cccc(Nc6ccccc6)c45

InChI

1S/2C16H13NO3S.Mg.H2O/c2*18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13;;/h2*1-11,17H,(H,18,19,20);;1H2/q;;+2;/p-2

InChI key

FBANPIUXAXTAFX-UHFFFAOYSA-L

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General description

ANSA (8-Anilino-1-naphthalenesulfonic acid) is a hydrophobic polarity sensitive fluorescent dye useful as a site probe to detect conformational changes in cell and micelle membranes and molecules such as proteins. ANSA is also used as a fluorescent probe for the estimation of the critical micelle concentration (CMC) of surfactants.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
BCCL1990
BCCC9821
BCCK8670
BCCK2567
BCBR1899V

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Stefan Kofler et al.
Journal of molecular biology, 422(1), 109-123 (2012-05-29)
The ability of pathogenesis-related proteins of family 10 to bind a broad spectrum of ligands is considered to play a key role for their physiological and pathological functions. In particular, Bet v 1, an archetypical allergen from birch pollen, is
Rebecca L Smathers et al.
PloS one, 7(6), e38459-e38459 (2012-06-16)
4-Hydroxynonenal (4-HNE) is a reactive α,β-unsaturated aldehyde produced during oxidative stress and subsequent lipid peroxidation of polyunsaturated fatty acids. The reactivity of 4-HNE towards DNA and nucleophilic amino acids has been well established. In this report, using proteomic approaches, liver
Chang Li et al.
International journal of biological macromolecules, 49(5), 910-916 (2011-08-23)
In our study, we showed that at a relatively low concentration, H(2)O(2) can irreversibly inactivate the human brain type of creatine kinase (HBCK) and that HBCK is inactivated in an H(2)O(2) concentration-dependent manner. HBCK is completely inactivated when incubated with
James A McLure et al.
Drug metabolism and disposition: the biological fate of chemicals, 39(9), 1711-1717 (2011-05-26)
The fluorescence of 1-anilinonaphthalene-8-sulfonate (ANS) in the presence of human liver microsomes (HLMs) is altered by drugs that bind nonspecifically to the lipid bilayer. The present study characterized the relationship between the nonspecific binding (NSB) of drugs to HLMs as
Clare A Peters Libeu et al.
PloS one, 7(6), e40027-e40027 (2012-07-07)
One of the events associated with Alzheimer's disease is the dysregulation of α- versus β-cleavage of the amyloid precursor protein (APP). The product of α-cleavage (sAPPα) has neuroprotective properties, while Aβ1-42 peptide, a product of β-cleavage, is neurotoxic. Dimerization of
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