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Merck
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Key Documents

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11-0398

Sigma-Aldrich

Fluorescamine

≥98.0%

Sinónimos:

4-Phenylspiro-[furan-2(3H),1-phthalan]-3,3′-dione

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About This Item

Fórmula empírica (notación de Hill):
C17H10O4
Número de CAS:
38183-12-9
Peso molecular:
278.26
Beilstein/REAXYS Number:
921143
EC Number:
253-814-5
MDL number:
MFCD00005928
UNSPSC Code:
12191502
PubChem Substance ID:
329749297

assay

≥98.0%

availability

available only in Japan

mp

153-157 °C (lit.)

SMILES string

O=C1OC2(OC=C(C2=O)c3ccccc3)c4ccccc14

InChI

1S/C17H10O4/c18-15-13(11-6-2-1-3-7-11)10-20-17(15)14-9-5-4-8-12(14)16(19)21-17/h1-10H

InChI key

ZFKJVJIDPQDDFY-UHFFFAOYSA-N

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Application

Non-fluorescent reagent that reacts readily under mild conditions with primary amines in amino acids and peptides to form stable, highly fluorescent compounds. Low background due to hydrolysis. Useful for the fluorometric assay of amino acids, protein, and proteolytic enzymes. Effectively blocks newly generated amino termini in protein sequence analyses.

Suitability

for HPLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Amit K Jha et al.
Biomaterials, 32(10), 2466-2478 (2011-01-11)
We have created hyaluronic acid (HA)-based, cell-adhesive hydrogels that direct the initial attachment and the subsequent differentiation of human mesenchymal stem cells (MSCs) into pre-osteoblasts without osteogenic supplements. HA-based hydrogel particles (HGPs) with an average diameter of 5-6 μm containing
Min Jia et al.
Analytical chemistry, 81(19), 8033-8040 (2009-10-01)
Fluorescamine derivatized 3-amino-2,2,5,5,-tetramethyl-1-pyrrolidinyloxy (I) is shown to undergo an irreversible reaction with peroxyl radicals and other radical oxidants to generate a more highly fluorescent diamagnetic product (II) and thus can be used as a highly sensitive and versatile probe to
Manjeet Deshmukh et al.
Biomaterials, 31(26), 6675-6684 (2010-06-22)
Two vinyl sulfone functionalized crosslinkers were developed for the purpose of preparing degradable poly(ethylene glycol) (PEG) hydrogels (EMXL and GABA-EMXL hydrogels). A self-elimination degradation mechanism in which an N-terminal residue of a glutamine is converted to pyroglutamic acid with subsequent
Zeynep Aydoğmuş
Journal of fluorescence, 19(4), 673-679 (2009-02-03)
A new, simple and sensitive spectrofluorimetric method has been developed for the determination of oseltamivir phosphate (OSP) in capsules. The method is based on the reaction between oseltamivir and fluorescamine in borate buffer solution of pH 8.50 to give highly
Wen-Hsien Tsai et al.
Journal of chromatography. A, 1217(49), 7812-7815 (2010-11-04)
A simple sugaring-out assisted liquid-liquid extraction method combined with high-performance liquid-chromatography with fluorescence detection (HPLC-FL) was developed for the extraction and determination of sulfonamides in honey. Sample preparation consisted of acid hydrolysis to release sugar-bound sulfonamides. After derivatization with fluorescamine
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