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Merck
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Key Documents

ABS102

Sigma-Aldrich

Anti-AKAP 79 Antibody

from rabbit, purified by affinity chromatography

Sinónimos:

A-kinase anchor protein 5, AKAP-5, A-kinase anchor protein 79 kDa, AKAP 79, H21, cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

western blot: suitable

NCBI accession no.

NP_004848

UniProt accession no.

P24588

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... AKAP5(9495)

General description

A-kinase anchoring protein 79 (AKAP 79) is a scaffolding protein that resides predominantly in excitatory neuronal synapses. AKAP 79 interacts with membrane-associated guanylate kinase (MAGUK) to be used by glutamate receptors. AKAP 79 may also be involved with SAP97 and other large signaling complexes. AKAP 79 is essential for forskolin-induced up-regulation of L-current.

Specificity

This antibody recognizes AKAP 79 at the C-terminus.

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human AKAP 79.

Application

Detect AKAP 79 using this Anti-AKAP 79 Antibody validated for use in WB.

Quality

Evaluated by Western Blot in HEK293 cell lysate with overexpressed N-terminal Flag-AKAP79.

Western Blot Analysis: 1 µg/mL of this antibody detected AKAP 79 on 10 µg of HEK293 cell lysate with overexpressed N-terminal Flag-AKAP79.

Target description

~79 kDa observed.
AKAP79 migrates in WB with an apparent molecular weight of ~79 kDa Uncharacterized bands appear at ~35 kDa and ~13 kDa in some lysates.

Analysis Note

Control
HEK293 cell lysate with overexpressed N-terminal Flag-AKAP79

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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