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Merck
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Key Documents

07-674

Sigma-Aldrich

Anti-Na+K+ ATPase α-2 Antibody

serum, Upstate®

Sinónimos:

Anti-Anti-DEE98, Anti-Anti-FARIMPD, Anti-Anti-FHM2, Anti-Anti-MHP2

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_000702.2

UniProt accession no.

P50993

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... ATP1A2(477)

Specificity

Na+/K+ ATPase α-2
Predicted to crossreact with human, mouse, dog and monkey based on sequence homology.

Immunogen

KLH-conjugated, synthetic peptide (CKAGQENISVSKRDT) corresponding to amino acids 432-445 of human Na+K+ ATPase α-2, with an N-terminal cysteine added for conjugation purposes.

Application

Anti-Na+K+ ATPase α-2 Antibody is an antibody against Na+K+ ATPase α-2 for use in WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Quality

Routinely evaluated by immunoblot with rat brain microsomal preparation (catalog# 12-144)

Target description

Mr 105kDa

Physical form

Antiserum

Storage and Stability

Stable for 2 years at -20°C from date of shipment

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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K Taniguchi et al.
Journal of biochemistry, 129(3), 335-342 (2001-02-28)
Since the discovery of Na/K-ATPase, evidence has accumulated to suggest that 1 mol of ATP hydrolysis occurs via the Na(+)-occluded ADP-sensitive phosphoenzyme, the K(+)-sensitive phosphoenzyme and the K(+)-occluded enzyme accompanying active transport of 3Na(+) and 2K(+) according the Post-Albers scheme.
Post-ischemic stimulation of 2-deoxyglucose uptake in rat myocardium: role of translocation of Glut-4
Montessuit, C, et al
Journal of Molecular and Cellular Cardiology, 30, 393-403 (1998)
The Na, K-ATPase in the failing human heart.
Schwinger, Robert H G, et al.
Cardiovascular Research, 57, 913-920 (2003)
Na(+), K(+)-ATPase: the new face of an old player in pathogenesis and apoptotic/hybrid cell death.
Yu, Shan Ping
Biochemical Pharmacology, 66, 1601-1609 (2003)
Modulation of endothelial cell KCa3.1 channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries.
Dora, KA; Gallagher, NT; McNeish, A; Garland, CJ
Circulation Research null
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