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P-080

Supelco

Phenazepam solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C15H10N2OBrCl
Número de CAS:
51753-57-2
Peso molecular:
349.61
EC Number:
200-835-2
MDL number:
MFCD00423674
UNSPSC Code:
41116107
PubChem Substance ID:
329820057
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

Clc1ccccc1C2=NCC(=O)Nc3ccc(Br)cc23

InChI

1S/C15H10BrClN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20)

InChI key

CGMJQQJSWIRRRL-UHFFFAOYSA-N

General description

Phenazepam, a benzodiazepine drug produced in Russia, is used in Europe as an anxiolytic, anticonvulsant, and muscle relaxant. Although not used therapeutically in the US, the drug can be purchased on the internet for “laboratory research” purposes. Cases of abuse have been reported from European countries such as Sweden and Russia to states including New York, Kentucky, North Carolina, and Georgia.

Application


  • Advancements in Designer Benzodiazepine Detection: Phenazepam is included in studies aiming to advance the detection of designer benzodiazepines, contributing significantly to forensic and clinical toxicology (Wu and Fu, 2022).

  • Neuroactive Substance Monitoring: Phenazepam′s detection trends were studied in the context of new psychoactive substance monitoring, reflecting its ongoing surveillance and public health implications in Australia (Syrjanen et al., 2023).

  • Pharmacological Analysis of GABA(A) Receptors: A comprehensive pharmacological analysis was conducted on Phenazepam among other ligands, investigating its anxiolytic, anticonvulsant, and hypnotic properties through GABA(A) receptor modulation (Voronin et al., 2023).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Muta. 1B

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

L N Pavlov et al.
Radiatsionnaia biologiia, radioecologiia, 52(4), 388-393 (2012-10-05)
Effects of EMR on the behavior of Wistar rats (196 males, 180-240 g of mass) under the conflict of opposed motivations: strong positive, drinking, motivation, and strong negative, pain, motivation were studied. The animals were exposed to low intensity EMR
N G Bogdan et al.
Eksperimental'naia i klinicheskaia farmakologiia, 74(8), 8-12 (2012-01-12)
The influence of the selective anxiolytic drug afobazole in a single dose of 10 mg on the psychophysiological functions of healthy volunteers was studied in laboratory experiments. It is established that afobazole optimizes some psychophysiological characteristics of stress-labile individuals and
V N Fedorets
Advances in gerontology = Uspekhi gerontologii, 24(1), 154-161 (2011-08-04)
833 patients aged 32 to 74 years who had coronary heart disease (CHD) were examined. Psychosocial and clinicofunctional features typical for elderly people of behavioral type A and with diagnosed CHD and ways for treatment optimization and disease prophylaxis are
[Pharmacologic correction of psycho-emotional status of patients with thyroid nodules in the preoperative period].
E M Zvukova et al.
Voprosy onkologii, 56(6), 722-725 (2010-01-01)
Paul I Dargan et al.
European journal of clinical pharmacology, 69(3), 361-363 (2012-07-31)
There is increasing evidence from around Europe of the availability and misuse of long-acting benzodiazepines such as phenazepam. There is little information on the acute toxicity of these compounds; we describe here a case of analytically confirmed phenazepam-related acute toxicity.
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