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I-034

Supelco

Human Insulin solution

100 μg/mL in PBS, pH 7.2, certified reference material, ampule of 100 μL, Cerilliant®

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About This Item

Fórmula empírica (notación de Hill):
C257H383N65O77S6
Número de CAS:
Peso molecular:
5807.57
Código UNSPSC:
41116107
NACRES:
NA.24
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grado

certified reference material

Nivel de calidad

Formulario

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

envase

ampule of 100 μL

fabricante / nombre comercial

Cerilliant®

concentración

100 μg/mL in PBS, pH 7.2

técnicas

liquid chromatography (LC): suitable

aplicaciones

clinical testing

Formato

single component solution

temp. de almacenamiento

−20°C

Clave InChI

PBGKTOXHQIOBKM-FHFVDXKLSA-N

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Descripción general

Human insulin is a peptide hormone, composed of 51 amino acids, produced by beta cells of the pancreatic islets. Insulin regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of, especially glucose from the blood into liver, fat and skeletal muscle cells. Insulin levels are routinely measured to evaluate insulin production; diagnose insulin-producing tumors; determine hypoglycemia or to identify insulin resistance. This certified Snap-N-Spike® solution of the fully-intact human insulin protein is suitable for use as starting material in calibrators and controls in LC-MS/MS insulin testing methods.
The Recombinant Human Insulin in phosphate buffered saline (PBS), pH 7.2 (solution) is a standard that fulfills the criteria set by ISO for a certified reference material and a primary standard. It is traceable to the SI and higher order standards through a continuous series of comparisons.

Aplicación

Human Insulin solution is suitable for the in vitro identification, calibration, and quantification of the analyte(s) in analytical and R&D applications.

Características y beneficios

  • The active insulin content is determined through quantitative amino acid analysis (AAA) and chromatographic purity.
  • Each raw material used in the standard has undergone identification and thorough characterization using multiple analytical techniques.
  • A Mass Balance Purity Factor is assigned to each raw material.
  • The standard is prepared using balances that are fully qualified and calibrated to meet ISO 17025 requirements.
  • The standard is prepared and certified under the ISO 17034, ISO/IEC 17025, ISO 9001, and ISO 13485 standards.

Nota de preparación

  • Thaw the product at refrigerator or room temperature.
  • Mix well before use.
  • Once thawed, do not refreeze the product.
  • Use established good laboratory practices to quantitatively transfer the desired volume and spike the product into a matrix or dilute it to the desired concentration.

Otras notas

This product′s purpose is for testing. THIS PRODUCT IS NOT INTENDED FOR HUMAN OR THERAPEUTIC USE. Please refer to the safety data sheet for specific details regarding any possible hazards and necessary precautions.

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

nwg

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Questions

  1. Is this solution stable if left at room temperature for ~ 24 hours? It was stored at -70C before and then put back into -70C after ~24 hours at room temperature.

    1 answer
    1. Once thawed, this product may not be refrozen.

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