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Merck

860525P

Avanti

C24:1 Ceramide (d18:1/24:1(15Z))

Avanti Research - A Croda Brand

Sinónimos:

N-nervonoyl-D-erythro-sphingosine

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About This Item

Fórmula empírica (notación de Hill):
C42H81NO3
Número de CAS:
Peso molecular:
648.10
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (860525P-10mg)
pkg of 1 × 25 mg (860525P-25mg)
pkg of 1 × 5 mg (860525P-5mg)
pkg of 1 × 50 mg (860525P-50mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C42H81NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-42(46)43-40(39-44)41(45)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,35,37,40-41,44-45H,3-16,19-34,36,38-39H2,1-2H3,(H,43,46)/b18-17-,37-35+/t40-,41+/m0/s1

InChI key

VJSBNBBOSZJDKB-KPEYJIHVSA-N

Categorías relacionadas

General description

Ceramides comprise spingolipids with acyl chains of C14 to C24 saturated and monounsaturated fatty acids. They are present in most of the mammalian tissues.

Application

C24:1 Ceramide (d18:1/24:1(15Z)) has been used as an internal stand in liquid chromatography-mass spectrometer. It is also suitable for use as a standard in high-performance liquid chromatography/tandem mass spectrometry.

Biochem/physiol Actions

Ceramide (d18:1/24:1[15Z]) levels are elevated inprimary open angle glaucoma (POAG). It is a biomarker for the human arterial tissue and plasma major adverse cardiac and cerebrovascular events (MACE). In general, ceramides are key second messengers in sphingomyelin pathway and modulate the pathophysiology of metabolic diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (860525P-10mg)
5 mL Amber Glass Screw Cap Vial (860525P-25mg)
5 mL Amber Glass Screw Cap Vial (860525P-50mg)
5 mL Amber Glass Screw Cap Vial (860525P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Plasma ceramides as prognostic biomarkers and their arterial and myocardial tissue correlates in acute myocardial infarction
de Carvalho LP, et al.
JACC. Basic to translational science, 3(2), 163-175 (2018)
Human trabecular meshwork sphingolipid and ceramide profiles and potential latent fungal commensalism
Aljohani AJ, et al.
Investigative Ophthalmology & Visual Science, 55(6), 3413-3422 (2014)
Atypical surface behavior of ceramides with nonhydroxy and 2-hydroxy very long-chain (C28-C32) PUFAs
Penalva DA, et al.
Biochimica et Biophysica Acta - Biomembranes, 1838(3), 731-738 (2014)
Hypothalamic AMPK-ER stress-JNK1 axis mediates the central actions of thyroid hormones on energy balance
Martinez-Sanchez N, et al.
Cell Metabolism, 26(1), 212-229 (2017)
Increased ceramide content and NFkappaB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males
Rivas DA, et al.
Journal of Applied Physiology, 113(11), 1727-1736 (2012)

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