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Merck

840034P

Avanti

16:0-18:1 PS (POPS)

Avanti Research - A Croda Brand

Sinónimos:

1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); POPS; PS(16:0/18:1(9Z)); 110669

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About This Item

Fórmula empírica (notación de Hill):
C40H75NO10PNa
Número de CAS:
Peso molecular:
783.99
Número MDL:
Código UNSPSC:
51191904
NACRES:
NA.25

descripción

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt)

Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 10 mg (840034P-10mg)
pkg of 2 × 100 mg (840034P-200mg)
pkg of 5 × 100 mg (840034P-500mg)
pkg of 1 × 25 mg (840034P-25mg)

fabricante / nombre comercial

Avanti Research - A Croda Brand

tipo de lípido

phospholipids
cardiolipins

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

Clave InChI

RQYKXRYGZHMUSU-JEAFVVATSA-M

Descripción general

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.

Aplicación

16:0-18:1 PS (POPS) has been used:
  • in phospholipid mixture for nanodisc preparation
  • in liposome preparation
  • in lipid vesicle preparation for surface plasmon resonance (SPR) analysis

Acciones bioquímicas o fisiológicas

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It has the ability to cross the blood-brain barrier. It plays a key role in the formation of short-term memory, the ability to create new memories, to focus attention, to reason and solve problems and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.

Envase

5 mL Clear Glass Sealed Ampule (840034P-10mg)
5 mL Clear Glass Sealed Ampule (840034P-200mg)
5 mL Clear Glass Sealed Ampule (840034P-25mg)
5 mL Clear Glass Sealed Ampule (840034P-500mg)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Visite la Librería de documentos

Fluorophore Labeling, Nanodisc Reconstitution and Single-molecule Observation of a G Protein-coupled Receptor
Lamichhane R, et al.
Bio-protocol, 7(12) (2017)
Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3, 4, 5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain
Kim E, et al.
Cellular Signalling, 51, 130-138 (2018)
Josef Melcr et al.
Journal of chemical theory and computation, 16(1), 738-748 (2019-11-26)
Phosphatidylserine (PS) lipids are important signaling molecules and the most common negatively charged lipids in eukaryotic membranes. The signaling can be often regulated by calcium, but its interactions with PS headgroups are not fully understood. Classical molecular dynamics (MD) simulations
Examination of the Interaction between a Membrane Active Peptide and Artificial Bilayers by Dual Polarisation Interferometry
Payne JAE, et al.
Bio-protocol, 7(1), e2087-e2087 (2017)
Kari Kusler et al.
The journal of physical chemistry. B, 120(50), 12883-12889 (2016-12-14)
Phosphatidylserine (PS) has previously been found to bind Cu2+ in a ratio of 1 Cu2+ ion per 2 PS lipids to form a complex with an apparent dissociation constant that can be as low as picomolar. While the affinity of

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