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830856P

Avanti

17:0 PA

1,2-diheptadecanoyl-sn-glycero-3-phosphate (sodium salt), powder

Sinónimos:

PA(17:0/17:0)

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About This Item

Fórmula empírica (notación de Hill):
C37H72O8PNa
Número de CAS:
154804-54-3
Peso molecular:
698.93
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (830856P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 830856P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C37H73O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36(38)43-33-35(34-44-46(40,41)42)45-37(39)32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h35H,3-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/t35-;/m1./s1

InChI key

IAELRFKIVVBNTO-RUQJKXHKSA-M

General description

Phosphatidic acid (PA), a phospholipid is a minor component of the phospholipid pool. It is made up of two fatty acids and a phosphate group and are covalently attached with the help of ester linkage to a glycerol molecule. PA is an important constituent of cell membranes.

Application

17:0 PA has been used as an internal standard for BXD liver samples/lipidomics analysis and as an internal standard for BXD plasma sample analysis. It may be used as a component in internal standard mix to spike the brain tissue homogenate.

Biochem/physiol Actions

Phosphatidic acid (PA) serves as a lipid messenger. It can enhance the production of muscle protein. PA can also serve as a signaling lipid. It plays a key role in mammalian target of rapamycin (mTOR) signaling.

Packaging

5 mL Amber Glass Screw Cap Vial (830856P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Sophie Ayciriex et al.
Frontiers in molecular neuroscience, 10, 211-211 (2017-07-27)
Impairment in cholesterol metabolism is associated with many neurodegenerative disorders including Alzheimer's disease (AD). However, the lipid alterations underlying neurodegeneration and the connection between altered cholesterol levels and AD remains not fully understood. We recently showed that cholesterol accumulation in
Yoshibumi Shimizu et al.
Prostaglandins & other lipid mediators, 150, 106450-106450 (2020-04-17)
Cyclic phosphatidic acid (cPA) is a lysophospholipid mediator that suppresses cancer metastasis and osteoarthritis. It also has neuroprotective roles in diseases such as multiple sclerosis and delayed neuronal death following transient ischemia. In order to take advantage of the properties
Pooja Jha et al.
Cell systems, 6(6), 722-733 (2018-06-18)
The genetics of individual lipid species and their relevance in disease is largely unresolved. We profiled a subset of storage, signaling, membrane, and mitochondrial liver lipids across 385 mice from 47 strains of the BXD mouse population fed chow or
Emily L Gill et al.
Journal of proteome research, 19(1), 424-431 (2019-11-13)
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain, as well as the degeneration of motor and nonmotor circuitries. The cause of neuronal death is currently unknown, although chronic
Pooja Jha et al.
Cell systems, 6(6), 709-721 (2018-06-18)
The genetic regulation and physiological impact of most lipid species are unexplored. Here, we profiled 129 plasma lipid species across 49 strains of the BXD mouse genetic reference population fed either chow or a high-fat diet. By integrating these data with genomics
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