452823

(+)-Bis[(R)-1-phenylethyl]amine

99%

• Sinónimos: (+)-Bis[(R)-α-methylbenzyl]amine, [R-(R*,R*)]-(+)-Bis(α-methylbenzyl)amine
• Fórmula lineal: [C₆H₅CH(CH₃)]₂NH
• Número de CAS: 23294-41-9
• Peso molecular: 225.33
• Beilstein/REAXYS Number: 3590931
• MDL number: MFCD00243088
• UNSPSC Code: 12352116
• PubChem Substance ID: 24868728
• NACRES: NA.22

Propiedades

• assay: 99%
• optical activity: [α]20/D +199.0°, neat
• optical purity: ee: ≥99% (GLC)
• refractive index: n20/D 1.5523 (lit.)
• bp: 86 °C/0.05 mmHg (lit.)
• density: 0.985 g/mL at 25 °C (lit.)
• SMILES string: C[C@@H](N[C@H](C)c1ccccc1)c2ccccc2
• InChI: 1S/C16H19N/c1-13(15-9-5-3-6-10-15)17-14(2)16-11-7-4-8-12-16/h3-14,17H,1-2H3/t13-,14-/m1/s1
• InChI key: NXLACVVNHYIYJN-ZIAGYGMSSA-N

Descripción

Application

(+)-Bis[(R)-1-phenylethyl]amine can be used:

• In the synthesis of β-amino acids.
• In the preparation of chiral C(19)-C(26) and C(27)-C(32) moieties of scytophycin C.
• To induce enantioselectivity in the deprotonation of prochiral ketones.
• As a starting material for the synthesis of chiral phenolate ligands through Mannich condensation reaction.
• In the synthesis of chiral phosphoramidite ligands.
• To prepare chiral cyclic isoimidium salts, which are further used to synthesize chiral lactones through Diels-Alder reaction.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: >235.4 °F - closed cup
• flash_point_c: > 113 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter