206490

4-Ethynylanisole

97%

• Sinónimos: 1-Ethynyl-4-methoxybenzene
• Fórmula lineal: CH₃OC₆H₄C≡CH
• Número de CAS: 768-60-5
• Peso molecular: 132.16
• Número MDL: MFCD00168815
• Código UNSPSC: 12352100
• ID de la sustancia en PubChem: 24852402
• NACRES: NA.22

Propiedades

• Ensayo: 97%
• Formulario: solid
• índice de refracción: n20/D 1.563 (lit.)
• bp: 87-91 °C/11 mmHg (lit.)
• mp: 28-29 °C (lit.)
• densidad: 1.019 g/mL at 25 °C (lit.)
• cadena SMILES: COc1ccc(cc1)C#C
• InChI: 1S/C9H8O/c1-3-8-4-6-9(10-2)7-5-8/h1,4-7H,2H3
• Clave InChI: KBIAVTUACPKPFJ-UHFFFAOYSA-N

Descripción

Descripción general

4-Ethynylanisole forms the corresponding propargyl aldehyde in good yield directly from DMF-dimethyl acetal without the need for making an acetylide salt. 1,3-dipolar cycloaddition of acceptor-cyclopropylmethylsilanes affords functionalized cyclopentenes in good yields.

4-Ethynylanisole can be used as a building block in organic synthesis and also used in sonogashira coupling reactions.

Aplicación

1,3-dipolar cycloaddition of acceptor-cyclopropylmethylsilanes affords functionalized cyclopentenes in good yields.

4-Ethynylanisole was used:

• in the synthesis of photoluminescent 1,2-dihydrophosphinines via a [4 + 2] cycloaddition
• along with an arylboronic acid and sodium azide in a copper-catalyzed, three-component synthesis of trisubstituted 1,2,4-triazoles
• in a study of a gold (III)-catalyzed hydroamination of alkynes leading to N-vinylindoles.

Forms the corresponding propargyl aldehyde in good yield directly from DMF-dimethyl acetal without the need for making an acetylide salt.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): 179.6 °F - closed cup
• Punto de inflamabilidad (°C): 82 °C - closed cup
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)