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Key Documents

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199222

Sigma-Aldrich

Chromone

99%

Sinónimos:

1-Benzopyran-4-one

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About This Item

Fórmula empírica (notación de Hill):
C9H6O2
Número de CAS:
491-38-3
Peso molecular:
146.14
EC Number:
207-737-9
MDL number:
MFCD00024064
UNSPSC Code:
12352100
PubChem Substance ID:
24851900
NACRES:
NA.22

assay

99%

mp

55-60 °C (lit.)

SMILES string

O=C1C=COc2ccccc12

InChI

1S/C9H6O2/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H

InChI key

OTAFHZMPRISVEM-UHFFFAOYSA-N

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General description

The compounds with chromone skeleton exhibits antiradical activities that provide protection against oxidative stress.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

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Aleksandra Kładna et al.
Luminescence : the journal of biological and chemical luminescence, 29(7), 846-853 (2014-02-01)
Recent reviews evidence that the naturally occurring compounds containing the chromone skeleton exhibit antiradical activities, providing protection against oxidative stress. The antioxidant activities of 13 new synthesized chromonyl-2,4-thiazolidinediones, chromonyl-2,4-imidazolidinediones and chromonyl-2-thioxoimidzolidine-4-ones were evaluated using in vitro antioxidant assays, including superoxide
Włodzimierz Lewandowski et al.
PloS one, 15(8), e0229477-e0229477 (2020-08-22)
The research was conducted in the "logical series" of seven ligands: chromone, flavone, 3-hydroxyflavone, 3,7-dihydroxyflavone, galangin, kaempferol and quercetin. Each subsequent ligand differs from the previous one, among others by an additional hydroxyl group. The studied chromone derivatives are plant
Xue Liang et al.
Journal of pharmacological sciences, 135(1), 14-21 (2017-09-21)
Metformin has received increasing attention for its potential anticancer activity against certain human leukemia cells, but its effects on human megakaryoblastic cells are unclear. This study aimed to investigate the effects of metformin on proliferation and apoptosis of human megakaryoblastic
João Guilherme de Moraes Pontes et al.
Scientific reports, 10(1), 13457-13457 (2020-08-12)
Huanglongbing (HLB) is a disease of worldwide incidence that affects orange trees, among other commercial varieties, implicating in great losses to the citrus industry. The disease is transmitted through Diaphorina citri vector, which inoculates Candidatus Liberibacter spp. in the plant
Miguel Pinto et al.
Pharmaceutics, 11(7) (2019-07-25)
The current pharmacological treatments for Parkinson's disease only offer symptomatic relief to the patients and are based on the administration of levodopa and catechol-O-methyltransferase or monoamine oxidase-B inhibitors (IMAO-B). Since the majority of drug candidates fail in pre- and clinical
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