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130249

Sigma-Aldrich

2-Nitrophenylacetic acid

98%

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About This Item

Fórmula lineal:
O2NC6H4CH2CO2H
Número de CAS:
3740-52-1
Peso molecular:
181.15
Beilstein/REAXYS Number:
1959243
EC Number:
223-128-0
MDL number:
MFCD00007190
UNSPSC Code:
12352100
PubChem Substance ID:
24847953
NACRES:
NA.22

assay

98%

form

solid

mp

137-140 °C (lit.)

SMILES string

OC(=O)Cc1ccccc1[N+]([O-])=O

InChI

1S/C8H7NO4/c10-8(11)5-6-3-1-2-4-7(6)9(12)13/h1-4H,5H2,(H,10,11)

Inchi Key

WMUZDBZPDLHUMW-UHFFFAOYSA-N

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Application

2-Nitrophenylacetic acid was used as an internal standard in the determination of the theophylline solubilizer salicylamide-O-acetic acid.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

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Leveraging a small-molecule modification to enable the photoactivation of rho GTPases.
Katryn R Harwood et al.
Chembiochem : a European journal of chemical biology, 10(18), 2855-2857 (2009-10-31)
H U Schulz et al.
Journal of pharmaceutical and biomedical analysis, 3(5), 469-475 (1985-01-01)
A high-performance liquid chromatographic method for the determination of the theophylline solubilizer salicylamide-O-acetic acid has been developed in the range 0.5 to 10 microg/ml for human serum and 5 to 400 microg/ml for urine. Reversed-phase ion-pair chromatography was employed with
M K Danks et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 5(4), 917-924 (1999-04-23)
Several recent studies have examined the possibility of producing tumor-specific cytotoxicity with various enzyme/ prodrug combinations. The enzymes are targeted to tumor cells either with antibodies (ADEPT, antibody directed enzyme prodrug therapy) or with viruses (VDEPT). The goal of the
Jan-Michael Mewes et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 12(11), 2077-2080 (2011-06-10)
Femtosecond spectroscopy and quantum chemical calculations provide detailed insights into the specificities of the uncaging mechanism of CO2 from ortho-, meta-, and para-nitrophenylacetate. The emerging general principles allow a rational design of improved ortho-nitrophenyl cages for chemical and biological applications.
Manuela F Frasco et al.
The FEBS journal, 274(7), 1849-1861 (2007-03-16)
The poorly known mechanism of inhibition of cholinesterases by inorganic mercury (HgCl2) has been studied with a view to using these enzymes as biomarkers or as biological components of biosensors to survey polluted areas. The inhibition of a variety of
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