1457301

Naproxen

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid
• Linear Formula: CH₃OC₁₀H₆CH(CH₃)CO₂H
• CAS Number: 22204-53-1
• Molecular Weight: 230.26
• Beilstein: 3591068
• MDL number: MFCD00010500
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750529
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: naproxen
• manufacturer/tradename: USP
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• mp: 152-154 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
• InChI: 1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
• InChI key: CMWTZPSULFXXJA-VIFPVBQESA-N
• Gene Information: human ... PTGS1(5742) , PTGS2(5743)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Naproxen USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Dexamethasone Compounded Oral Suspension
• Naproxen
• Naproxen Compounded Oral Suspension
• Naproxen Delayed-Release Tablets
• Naproxen Oral Suspension
• Naproxen Tablets
• Terazosin Tablets

Biochem/physiol Actions

Non-selective cyclooxygenase (COX-1 and COX-2) inhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08,GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335,H361fd,H411
• Precautionary Statements: P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3