Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

04238

Sigma-Aldrich

Hydroxyapatite

puriss., meets analytical specification of Ph. Eur., BP, FCC, E341, ≥90% (calculated on glowed substance)

Synonym(s):

Calcium phosphate hydroxide, Durapatite, Hydroxylapatite

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
3Ca3(PO4)2 · Ca(OH)2
CAS Number:
1306-06-5
Molecular Weight:
502.31
EC Number:
215-145-7
MDL number:
MFCD00010904
UNSPSC Code:
41116107
PubChem Substance ID:
57646735
NACRES:
NA.21
Pricing and availability is not currently available.

grade

puriss.

Quality Level

200

Assay

≥90% (calculated on glowed substance)

form

powder

quality

meets analytical specification of Ph. Eur., BP, FCC, E341

composition

Ca, 35-40%

impurities

residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.2% insoluble in HCl

loss

≤8% loss on ignition, 800 °C

anion traces

chloride (Cl-): ≤1500 mg/kg
fluoride (F-): ≤50 mg/kg
sulfate (SO42-): ≤5000 mg/kg

cation traces

As: ≤2 mg/kg
Cd: ≤1 mg/kg
Cu: ≤20 mg/kg
Fe: ≤400 mg/kg
Hg: ≤1 mg/kg
Pb: ≤2 mg/kg
Zn: ≤20 mg/kg

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

Looking for similar products? Visit Product Comparison Guide

Application


  • New Physico-Chemical Analysis of Magnesium-Doped Hydroxyapatite in Dextran Matrix Nanocomposites.: This research article focuses on the development and characterization of magnesium-doped hydroxyapatite within a dextran matrix, emphasizing its potential applications in biomedical and tissue engineering fields (Predoi et al., 2023).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCK3981
BCCK3789
BCCG0883
BCCF4218
BCCD1627

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chemical characterization of silicon-substituted hydroxyapatite
Gibson I, et al.
Journal of Biomedical Materials Research, 44(4), 422-428 (1999)
Mechanical properties of sintered hydroxyapatite for prosthetic applications.
Akao M ,et al.
J. Mater. Sci., 16(3), 809-812 (1981)
P Ducheyne et al.
Biomaterials, 7(2), 97-103 (1986-03-01)
Hydroxyapatite from two sources was electrophoretically deposited onto flat titanium plate material. Depending upon the deposition conditions various changes in the structure of the ceramic were identified. A well-adhering Ti-P compound was present at the interface. Hydroxyapatite oxygenated to various
Sophie E P New et al.
Circulation research, 113(1), 72-77 (2013-04-26)
We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. We tested the hypothesis that macrophage-derived MVs contribute
H S Alghamdi et al.
Journal of dental research, 92(11), 982-988 (2013-09-24)
Osteoporotic conditions are anticipated to affect the osseointegration of dental implants. This study aimed to evaluate the effect of a radiofrequent magnetron-sputtered calcium phosphate (CaP) coating on dental implant integration upon installment in the femoral condyles of both healthy and
View All Related Papers

Questions

  1. What is the particle size of this product?

    1 answer

    1. The particle size for this product is not determined. However, other hydroxyapatite products may be of interest as the particle size is available:

      900203; Hydroxyapatite, powder, 10 μm, spec. surface area ≥80 m2/g
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/900203-BULKMKCT5305.pdf

      900204; Hydroxyapatite, powder, 5 μm, surface area ≥80 m2/g
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/900204-BULKMKCT6258.pdf

      Helpful?

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service