MAB1681
Anti-Vimentin Antibody, clone LN-6
culture supernatant, clone LN-6, Chemicon®
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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biological source
mouse
Quality Level
antibody form
culture supernatant
antibody product type
primary antibodies
clone
LN-6, monoclonal
species reactivity
human, mouse
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable (paraffin)
isotype
IgM
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... VIM(7431)
General description
Vimentin is a class III intermediate filament protein (homopolymers) found in various non-epithelial cells including mesenchymal cells and fibroblasts. In many cells of mesenchymal origin, it is one of the most prominent phosphoproteins, especially during cell division when enhanced phosphorylation of vimentin corresponds with the reorganization of vimentin filaments.
Specificity
Reacts with human mesenchymal cells and derived sarcomas. Reacts with an epitope of the cytoskeletal protein vimentin but unlike other vimentin antibodies, does not react with human lymphoid cells or derived malignancies. Reactive with endothelium, muscle, fibroblasts, melanocytes, peripheral nerve, sertoli cells, kidney mesangial cells and tubules, osteoblasts and periosteum, non-hematopoietic tumors of mesenchymal origin (all sarcomas), meningiomas and melanomas.
Immunogen
Nuclei from adult human thymic biopsy specimens.
Application
Anti-Vimentin Antibody, clone LN-6 detects level of Vimentin & has been published & validated for use in IH(P).
Immunohistochemistry on B5 fixed, paraffin embedded tissue sections.
Target description
57-60 kDa
Physical form
Liquid tissue culture supernatant containing 0.02% sodium azide.
Analysis Note
Control
Hyperplastic lymph nodes.
Hyperplastic lymph nodes.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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