07-594
Anti-Histone H2A.Z Antibody
serum, Upstate®
Synonym(s):
Anti-H2A.Z-1, Anti-H2A.z, Anti-H2A/z, Anti-H2AFZ, Anti-H2AZ
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
packaging
antibody small pack of 25 μL
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
UniProt accession no.
shipped in
ambient
target post-translational modification
unmodified
Gene Information
human ... H2AFZ(3015)
Specificity
Broad species cross-reactivity is expected
C-terminus of histone H2A.Z
Immunogen
peptide containing the sequence SLIGKKGQQ, corres-ponding to the C-terminus of human histone H2A.Z
Application
Detect Histone H2A.Z also known as H2AZ histone with Anti-Histone H2A.Z Antibody (Rabbit Polyclonal Antibody), that has been demonstrated to work in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Quality
routinely evaluated by immunoblot on acid extracted proteins from HeLa cells and recombinant Histone H2A.Z (Catalog #14-597), no cross-reactivity with Histone H2A
Target description
16kDa
Physical form
0.05% sodium azide before the addition of glycerol to 30%
Serum
Storage and Stability
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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H2A.Z overexpression promotes cellular proliferation of breast cancer cells.
Amy Svotelis,Nicolas Gevry,Gilles Grondin,Luc Gaudreau
Cell Cycle null
Molecular cloaking of H2A.Z on mortal DNA chromosomes during nonrandom segregation.
Yang Hoon Huh,James L Sherley
Stem Cells null
Zenab F Mchaourab et al.
Scientific data, 5, 180030-180030 (2018-03-07)
The human K562 chronic myeloid leukemia cell line has long served as an experimental paradigm for functional genomic studies. To systematically and functionally annotate the human genome, the ENCODE consortium generated hundreds of functional genomic data sets, such as chromatin
Chunyuan Jin et al.
Nature genetics, 41(8), 941-945 (2009-07-28)
To understand how chromatin structure is organized by different histone variants, we have measured the genome-wide distribution of nucleosome core particles (NCPs) containing the histone variants H3.3 and H2A.Z in human cells. We find that a special class of NCPs
Characterization of the stability and folding of H2A.Z chromatin particles: implications for transcriptional activation.
Abbott, D W, et al.
The Journal of Biological Chemistry, 276, 41945-41949 (2001)
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