P-070

Progesterone-D₉ solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₂₁H₂₁O₂D₉
• CAS Number: 15775-74-3
• Molecular Weight: 323.52
• EC Number: 200-835-2
• MDL number: MFCD01317491
• UNSPSC Code: 41116107
• PubChem Substance ID: 329820051
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in acetonitrile
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing; clinical testing
• format: single component solution
• storage temp.: −20°C
• SMILES string: [2H]C1=C2C([2H])([2H])CC3C(CCC4(C)C3CC[C@]4([2H])C(=O)C([2H])([2H])[2H])C2(C)CC([2H])([2H])C1=O
• InChI: 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1/i1D3,4D2,8D2,12D,17D
• InChI key: RJKFOVLPORLFTN-PQIPVKAESA-N

Description

General description

Progesterone, a steroid hormone of the progestogen class, is used for hormone replacement therapy. This internal standard is applicable for progesterone testing or isotope dilution methods by GC/MS or LC/MS for endocrinology, female health testing or clinical chemistry.

Application

• Progesterone-D₉ solution for hormone research: Progesterone-D₉ is extensively used as an internal standard in pharmacokinetic studies to measure progesterone levels in biological samples using LC-MS/MS, enhancing the accuracy of hormonal assays critical for understanding progesterone′s role in various physiological processes (Sasaki et al., 2015).


• Stable isotope labeled progesterone for bioanalysis: As a stable isotope-labeled compound, Progesterone-D₉ is integral in mass spectrometry, providing a reliable standard for quantifying progesterone in complex biochemical assays, thus facilitating detailed studies on steroid metabolism and its implications.


• Deuterated progesterone for mass spectrometry: The application of Progesterone-D₉ in mass spectrometry enhances the precision of detecting and quantifying minute quantities of progesterone and its metabolites, which is crucial for drug development and therapeutic monitoring.


• Progesterone-D₉ in steroid metabolism studies: Utilized in research to understand the metabolic pathways of progesterone, Progesterone-D₉ helps in tracing the transformation and interaction of this hormone within the body, supporting advancements in reproductive health and disease treatment.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H319
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 35.6 °F - closed cup
• Flash Point(C): 2 °C - closed cup