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177377

Sigma-Aldrich

Diphenylcyclopropenone

98%

Synonym(s):

DPC

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About This Item

Empirical Formula (Hill Notation):
C15H10O
CAS Number:
Molecular Weight:
206.24
Beilstein:
608049
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

mp

118-122 °C (lit.)

SMILES string

O=C1C(c2ccccc2)=C1c3ccccc3

InChI

1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H

InChI key

HCIBTBXNLVOFER-UHFFFAOYSA-N

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General description

Diphenylcyclopropenone is a potent hapten. Its vibration frequency has been evaluated.

Application

Diphenylcyclopropenone was used in topical immunotherapy.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Yunseok Choi et al.
Annals of dermatology, 25(4), 434-439 (2013-12-29)
There exists a treatment challenge with periungual warts. Topical immunotherapy with diphenylcyclopropenone (DPCP) has recently been reported to be an effective treatment for recalcitrant warts, including periungual types. We aimed to evaluate the effectiveness and preference of topical immunotherapy with
T Kjeld et al.
Scandinavian journal of medicine & science in sports, 25(3), e253-e257 (2014-08-22)
Free diving is associated with extreme hypoxia. This study evaluated the combined effect of maximal static breath holding and underwater swimming on plasma biomarkers of tissue hypoxemia: erythropoietin, neuron-specific enolase and S100B, C-reactive protein, pro-atrial natriuretic peptide, and troponin T.
Valerio Tabacchini et al.
Physics in medicine and biology, 60(14), 5513-5525 (2015-07-03)
Gamma-ray detectors based on bright monolithic scintillation crystals coupled to pixelated photodetectors are currently being considered for several applications in the medical imaging field. In a typical monolithic detector, both the light intensity and the time of arrival of the
S von Moos et al.
Allergy, 67(5), 638-646 (2012-03-03)
Epicutaneous vaccination has gained increasing interest during the past decade as it offers a safe, needle-free, and patient-friendly alternative to invasive vaccine administrations. Recently, the safety and early efficacy of epicutaneous immunotherapy were also demonstrated in patients with hay fever
M C Ohlmeier et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 26(4), 503-507 (2011-05-17)
Although diphenylcyclopropenone (DCP) is frequently used for the treatment of alopecia areata (AA), large studies with more than 100 patients are still scarce. To determine the efficacy of DCP immunotherapy in a large cohort of patients with AA who had

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