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40060

Supelco

N-Nitrosodiphenylamine solution

certified reference material, 5000 μg/mL in methanol

Synonym(s):

N-Nitroso-N-phenylaniline, Diphenylnitrosamine, Diphenylnitrosoamine

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About This Item

CAS Number:
EC Number:
UNSPSC Code:
41116105

grade

certified reference material
TraceCERT®

Quality Level

Agency

EPA 625,8270,Mar ′90, Dec ′90, Aug ′91 Statement of Work
EPA OLM04 (Statement of Work)

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

concentration

5000 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

environmental

format

single component solution

storage temp.

2-8°C

InChI

1S/C12H10N2O/c15-13-14(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H

InChI key

UBUCNCOMADRQHX-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Flam. Liq. 2 - Skin Sens. 1 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F

Flash Point(C)

9.7 °C


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K E Appel et al.
Journal of cancer research and clinical oncology, 113(2), 131-136 (1987-01-01)
Nitrosodiphenylamine was tested for induction of DNA single strand breaks in rat hepatocytes and Chinese hamster V 79 cells with the alkaline filter elution assay. While in rat hepatocytes DNA damage was observed, negative results were obtained in V 79
K E Appel et al.
IARC scientific publications, (84)(84), 117-123 (1987-01-01)
The present paper deals with three aspects of cytochrome P450-dependent denitrosation of N-nitrosamines. (1) Nitrate was found in addition to nitrite as a metabolic product of the denitrosation reaction when N-nitrosamines were incubated with a microsomal system. This could also
[N-nitrosamines in the air of an enterprise producing rubber footwear and rubber technology articles].
L G Solenova et al.
Gigiena truda i professional'nye zabolevaniia, (6)(6), 23-25 (1990-01-01)
G A Westphal et al.
Archives of toxicology, 75(2), 118-122 (2001-05-17)
Dicyclohexylamine x nitrite is classified as an "experimental equivocal tumorigenic agent" by the National Toxicology Program. Since no genotoxic effects of the substance itself are known, the reported tumorigenic potential of dicyclohexylamine x nitrite could be due to generation of
J W Dallinga et al.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 10(3), 265-268 (2001-07-04)
The thermal energy analyser (TEA) is considered to be the gold standard for the determination of nitrosamines. However, since many laboratories cannot justify the use of such a very specific detection system, alternative detection methods are useful. While standard gas

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