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Astec® CHIROBIOTIC® TAG Chiral (5 μm) HPLC Columns

L × I.D. 15 cm × 2.1 mm, HPLC Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Astec® CHIROBIOTIC® TAG Chiral HPLC Column, 5 μm particle size, L × I.D. 15 cm × 2.1 mm

material

stainless steel column

Agency

suitable for USP L63

description

HPLC column

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-45 °C temperature
241 bar pressure (3500 psi)

technique(s)

HPLC: suitable
LC/MS: suitable

L × I.D.

15 cm × 2.1 mm

matrix

High-purity silica gel particle platform
fully porous particle

matrix active group

teicoplanin aglycone phase

particle size

5 μm

pore size

100 Å

operating pH range

3.0-6.8

separation technique

chiral

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General description

The removal of three carbohydrate moieties gives CHIROBIOTIC® TAG complementary selectivity to CHIROBIOTIC® T. Resolution is enhanced toward many of the amino acids, α, β, γ and cyclic, and especially sulfur-containing methionine, histidine and cysteine. A number of neutral molecules like the oxazolidinones, hydantoins and diazepines have shown enhanced resolution and, more remarkably, in the single solvents like methanol, ethanol and acetonitrile. Some acidic molecules have also shown increased selectivity.

  • Bonded phase: Teicoplanin aglycone
  • Operating pH range: 3.0 - 6.8
  • Particle diameter: 5, 10 or 16 μm
  • Pore size: 100 Å

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Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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Matthias Bechtold et al.
Journal of chromatography. A, 1113(1-2), 167-176 (2006-02-28)
The suitability of a teicoplanin-aglycone based chiral stationary phase for the simulated moving bed (SMB) enantioseparation of amino acids under enzyme-compatible conditions was shown following a procedure that is based solely on model-based simulations and HPLC experiments. A set of
Determination of eflornithine enantiomers in plasma, by solid-phase extraction and liquid chromatography with evaporative light-scattering detection
Malm, M., Bergqvist, Y.
Journal of Chromatography. B, Biomedical Sciences and Applications, 846 (1-2), 98-104 (2007)
Matthias Bechtold et al.
Journal of chromatography. A, 1154(1-2), 277-286 (2007-04-24)
Silica-bonded teicoplanin aglycone allows enantioseparation of amino acids by reversed-phase liquid chromatography with a low organic solvent content. However, a reversible change in the adsorption behavior leading to a retention time shift (RTS) was observed when a preparative scale column
Robert J Steffeck et al.
Journal of chromatography. A, 983(1-2), 91-100 (2003-02-06)
Ion-exclusion chromatography is a well established technique for the analysis of achiral ionic species, but it has rarely been applied to chiral analytes. In this paper enantioselective ion-exclusion separations were developed on two commercially available HPLC phases: Chirobiotic TAG, based
Burkholderia cepacia lipase is an excellent enzyme for the enantioselective hydrolysis of ?-heteroaryl-?-amino esters
Tasnadi, Gabor, et al.
Tetrahedron Asymmetry, 20 (15), 1771-1777 (2009)

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