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M3409

Sigma-Aldrich

Magnesium sulfate solution

for molecular biology, 1.00 M±0.04 M

Synonym(s):

Magnesium Sulphate, Magnesium(II) sulfate, MgSO4

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About This Item

Empirical Formula (Hill Notation):
MgSO4
CAS Number:
7487-88-9
Molecular Weight:
120.37
MDL number:
MFCD00011110
UNSPSC Code:
12352302
PubChem Substance ID:
24896841
NACRES:
NA.31
grade:
for molecular biology
form:
liquid
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grade

for molecular biology

Quality Level

200

sterility

0.2 μm filtered

form

liquid

concentration

1.00 M±0.04 M

cation traces

heavy metals (as Pb): ≤5 ppm

foreign activity

DNase, RNase, nickase and protease, none detected

SMILES string

[Mg++].[O-]S([O-])(=O)=O

InChI

1S/Mg.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2

InChI key

CSNNHWWHGAXBCP-UHFFFAOYSA-L

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Application

Magnesium sulfate solution has been used:
  • as a component in super optimal broth with catabolite repression (SOC) medium for culturing Escherichia coli[1]
  • as a component in transition media for culturing human umbilical vein endothelial cells (HUVEC)[2]]
  • as a component in M9 buffer for worm fixation prior to nuclei extraction[3]

Biochem/physiol Actions

Magnesium sulfate has anti-convulsant, anti-inflammatory and vasodilatory properties. Magnesium sulfate relaxes smooth muscles.[4] In acute asthma patients, use both intravenous and nebulization of magnesium sulfate as additive treatment improves pulmonary function.[4][5] Magnesium sulfate reduces preterm labor in high risk pregnant women.[4]

Preparation Note

Prepared in 18 megohm water

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000392448
0000372903
0000372904
0000358745
0000392448

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Method for multiplexing CRISPR/Cas9 in Saccharomyces cerevisiae using artificial target DNA sequences
Giersch RM and Finnigan GC
Bio-protocol, 7(18), 321-330 (2017)
RNA Chromatin Immunoprecipitation (RNA-ChIP) in Caenorhabditis elegans
Cecere G and Grishok A
Bio-protocol, 4(24), e1358-e1358 (2014)
The value of magnesium sulfate nebulization in treatment of acute bronchial asthma during pregnancy
Badawy MSH and Hassanin IMA
The Egyptian journal of chest diseases and tuberculosis, 63(2), 285-289 (2014)
Estrogen decreases TNF-alpha and oxidized LDL induced apoptosis in endothelial cells
Florian M and Magder S
Steroids, 73(1), 47-58 (2008)
Lex W Doyle et al.
Obstetrics and gynecology, 113(6), 1327-1333 (2009-05-23)
To systematically review rates of neurologic outcomes reported in childhood for the preterm fetus exposed to antenatal magnesium sulfate. We searched the Cochrane Pregnancy and Childbirth Group's Trials Register, CENTRAL (The Cochrane Library 2008, Issue 3), relevant references from retrieved
View All Related Papers

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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