31107-M

Ammonium chloride

puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5%

• Synonym(s): Salmiac
• Linear Formula: NH₄Cl
• CAS Number: 12125-02-9
• Molecular Weight: 53.49
• Beilstein: 4371014
• EC Number: 235-186-4
• MDL number: MFCD00011420
• UNSPSC Code: 12352300
• eCl@ss: 38050207
• PubChem Substance ID: 329753648
• NACRES: NA.21

Properties

• grade: ACS reagent; puriss. p.a.
• Quality Level: 100
• Agency: USP/NF; reag. ISO; reag. Ph. Eur.
• vapor density: 1.9 (vs air)
• vapor pressure: 1 mmHg ( 160.4 °C)
• Assay: ≥99.5%
• form: crystalline powder
• impurities: acidity or alkalinity, complies; bromides and iodides, complies; ≤0.005% insoluble matter
• pH: 4.5-5.5 (20 °C, 5%)
• mp: 340 °C (subl.) (lit.)
• anion traces: nitrate (NO₃^-): ≤5 mg/kg; phosphate (PO₄^3-): ≤2 mg/kg; sulfate (SO₄^2-): ≤20 mg/kg
• cation traces: As: ≤0.00005%; Ca: ≤0.0005%; Cu: ≤0.0002%; Fe: ≤0.0002%; K: ≤0.005%; Mg: ≤0.0005%; Na: ≤0.005%; Ni: ≤0.0001%; Pb: ≤0.0001%; Zn: ≤0.0002%; heavy metals: ≤5 mg/kg (by ICP-OES)
• suitability: complies for appearance of solution
• SMILES string: N.Cl
• InChI: 1S/ClH.H3N/h1H;1H3
• InChI key: NLXLAEXVIDQMFP-UHFFFAOYSA-N

Description

Application

Ammonium chloride can be used as a catalyst:

• To synthesize 3,4-dihydropyrimidin-2-(1H)-ones via solvent-free Biginelli condensation reaction.
• For the aldol condensation of carbonyl compounds.
• In the thia-Michael addition reaction of thiols to different α-enones.

It can also be used as:

• A promoter in the enantioselective hydrogenation of an unprotected β-enamine amides.
• A pH-adjuster in the preparation of waterborne glucose silicone resin.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H319
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable