05-920
Anti-NR2B Antibody, clone BWJHL
clone BWJHL, Upstate®, from mouse
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
BWJHL, monoclonal
species reactivity
human, rat
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
mouse ... Grin2B(14812)
Specificity
NR2B
Immunogen
GST fusion protein corresponding to residues 934-1457 of rat NR2B. Clone BWJHL.
Application
Anti-NR2B Antibody, clone BWJHL detects level of NR2B & has been published & validated for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Neurodegenerative Diseases
Neurochemistry & Neurotrophins
Neurodegenerative Diseases
Quality
routinely evaluated by immunoblot on rat brain microsomal preparations (Catalog#12-144)
Target description
Mr 180kDa
Physical form
Format: Purified
Protein G Purified
Storage and Stability
stable 2 years at -20°C from date of shipment
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Brain-derived neurotrophic factor-tyrosine kinase B pathway mediates NMDA receptor NR2B subunit phosphorylation in the supraoptic nuclei following progressive dehydration.
Carre?o, FR; Walch, JD; Dutta, M; Nedungadi, TP; Cunningham, JT
Journal of Neuroendocrinology null
Peter D Cole et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 19(16), 4446-4454 (2013-07-09)
To test whether memantine can prevent methotrexate-induced cognitive deficits in a preclinical model. After noting that methotrexate exposure induces prolonged elevations of the glutamate analog homocysteic acid (HCA) within cerebrospinal fluid, we tested whether intrathecal injection of HCA would produce
Jackson J Cone et al.
PloS one, 8(3), e58251-e58251 (2013-03-22)
The development of diet-induced obesity (DIO) can potently alter multiple aspects of dopamine signaling, including dopamine transporter (DAT) expression and dopamine reuptake. However, the time-course of diet-induced changes in DAT expression and function and whether such changes are dependent upon
Role of NR2B-type NMDA receptors in selective neurodegeneration in Huntington disease.
Li, Lijun, et al.
Neurobiology of Aging, 24, 1113-1121 (2003)
Sarah A Monaco et al.
Frontiers in cellular neuroscience, 12, 16-16 (2018-02-17)
Glycogen synthase kinase 3β (GSK3β) is a highly conserved serine/threonine kinase that has been implicated in both psychiatric and neurodegenerative diseases including schizophrenia, bipolar disorder, and Alzheimer's disease; therefore regulating its activity has become an important strategy for treatment of
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