850186P

08:0 PI(3,4,5)P3

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder

• Synonym(s): PIP3[3′,4′,5′](8:0/8:0); 110667
• Empirical Formula (Hill Notation): C₂₅H₆₂N₄O₂₂P₄
• CAS Number: 852043-38-0
• Molecular Weight: 894.67
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 100 μg (with stopper and crimp cap (850186P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850186P-500ug))
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 850186P
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]

Description

General description

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) is a less abundant lipid.

Application

08:0 PI(3,4,5)P3 may be used as a control compound for assessing phosphoinositide 3-kinase activity.

Biochem/physiol Actions

Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3), a lipid second messenger can modulate synaptic activity.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850186P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850186P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids