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About This Item
Linear Formula:
BrC6H3(F)NO2
CAS Number:
Molecular Weight:
220.00
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
96%
refractive index
n20/D 1.575 (lit.)
bp
240-241 °C (lit.)
mp
18-19 °C (lit.)
density
1.786 g/mL at 25 °C (lit.)
functional group
bromo
fluoro
nitro
SMILES string
[O-][N+](=O)c1cc(Br)ccc1F
InChI
1S/C6H3BrFNO2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H
InChI key
UQEANKGXXSENNF-UHFFFAOYSA-N
General description
4-Bromo-1-fluoro-2-nitrobenzene undergoes Sonogashira reaction with 2-fluoronitrobenzene to afford predominantly the bromo displacement product.
Application
4-Bromo-1-fluoro-2-nitrobenzene may be used in the synthesis of:
- 6-bromo-1H-benzo[d][1,2,3]triazol-1-ol
- 2-(4-bromo-2-nitrophenylamino)-5-methylthiophene-3-carbonitrile
- dibenzoxazepine analog, as potent sodium channel blocker
- 4-(4-bromo-2-nitrophenyl)piperazine-1-carboxylic acid tert-butylester
Used in the synthesis of anti-inflammatory agents.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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