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537373

Sigma-Aldrich

N,N-Dimethylacetoacetamide solution

80% in H2O

Synonym(s):

DMAA, N,N-Dimethyl-3-oxobutyramide

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About This Item

Linear Formula:
CH3COCH2CON(CH3)2
CAS Number:
Molecular Weight:
129.16
Beilstein:
1755038
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

concentration

80% in H2O

refractive index

n20/D 1.447

bp

105 °C

density

1.067 g/mL at 25 °C

SMILES string

CN(C)C(=O)CC(C)=O

InChI

1S/C6H11NO2/c1-5(8)4-6(9)7(2)3/h4H2,1-3H3

InChI key

YPEWWOUWRRQBAX-UHFFFAOYSA-N

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General description

The product is an 80% solution of N,N-dimethylacetoacetamide (DMAA) in water.

Application

  • Disposition and metabolism of N,N-dimethylacetoacetamide in male F344 and Wistar-Han rats and female B6C3F1 mice.: The research examines the metabolic pathways and disposition of N,N-dimethylacetoacetamide in different rat and mouse models, providing insights into its pharmacokinetic properties (Fennell T et al., 2011).
  • Reduction of ketones and alkyl iodides by SmI(2) and Sm(II)-HMPA complexes. Rate and mechanistic studies.: Explores the use of N,N-dimethylacetoacetamide in the reduction of ketones and alkyl iodides using samarium iodide complexes, providing detailed mechanistic insights into the reactions (Prasad E, Flowers RA 2nd, 2002).
  • Mechanistic study of beta-substituent effects on the mechanism of ketone reduction by SmI(2).: This study delves into the effects of beta-substituents on the reduction mechanisms of ketones using samarium iodide in the presence of N,N-dimethylacetoacetamide, elucidating critical aspects of the reaction dynamics (Prasad E, Flowers RA 2nd, 2002).

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

251.6 °F - closed cup

Flash Point(C)

122 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Bharathi Avula et al.
Journal of AOAC International, 98(3), 757-759 (2015-06-19)
The central nervous system stimulant 1,3-dimethylamylamine (DMAA) has been found in preworkout products and dietary supplements. A fast direct analysis in real time-quadrupole time of flight-MS method was used for identification of DMAA in dietary supplements and to determine if
Kyung Tai Lee et al.
Foot & ankle international, 35(12), 1329-1333 (2014-09-23)
Hallux valgus is speculated to increase the load on the second metatarsophalangeal (MTP) joint, possibly inducing degenerative osteoarthritis. In addition, the severity of arthritis may be correlated with the severity of hallux valgus. This study evaluated the association of arthritis
Sonia D'Souza et al.
Biomaterials, 35(35), 9447-9458 (2014-08-26)
The field of polymer-based membrane engineering has expanded since we first demonstrated the reaction of N-hydroxysuccinimide ester-terminated polymers with cells and tissues almost two decades ago. One remaining obstacle, especially for conjugation of polymers to cells, has been that exquisite
Marek Janko et al.
Biomacromolecules, 16(7), 2179-2187 (2015-06-24)
The properties of paper sheets can be tuned by adjusting the surface or bulk chemistry using functional polymers that are applied during (online) or after (offline) papermaking processes. In particular, polymers are widely used to enhance the mechanical strength of

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