124974

2-Chlorobenzaldehyde

99%

• Synonym(s): o-Chlorobenzaldehyde
• Linear Formula: ClC₆H₄CHO
• CAS Number: 89-98-5
• Molecular Weight: 140.57
• Beilstein: 385877
• EC Number: 201-956-3
• MDL number: MFCD00003304
• UNSPSC Code: 12352100
• eCl@ss: 39050404
• PubChem Substance ID: 24847637
• NACRES: NA.22

Properties

• vapor density: 4.84 (vs air)
• Quality Level: 100
• vapor pressure: 1.27 mmHg ( 50 °C)
• Assay: 99%
• autoignition temp.: 746 °F
• refractive index: n20/D 1.566 (lit.)
• bp: 209-215 °C (lit.)
• mp: 9-11 °C (lit.)
• density: 1.248 g/mL at 25 °C (lit.)
• SMILES string: [H]C(=O)c1ccccc1Cl
• InChI: 1S/C7H5ClO/c8-7-4-2-1-3-6(7)5-9/h1-5H
• InChI key: FPYUJUBAXZAQNL-UHFFFAOYSA-N

Description

General description

2-Chlorobenzaldehyde undergoes alkynylation with phenylacetylene in the presence of catalytic ligands and dimethylzinc at 0°C to form binaphthyl-derived amino alcohols.

Application

2-Chlorobenzaldehyde has been used in generation of small focused library of diversely functionalized dihydropyrimidine derivatives via one-pot three-component Biginelli cyclocondensation of β-ketoesters, aldehydes and thioureas.

Safety Information

• Pictograms: GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H314,H317
• Precautionary Statements: P261 - P272 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 2
• Flash Point(F): 206.6 °F - closed cup
• Flash Point(C): 97 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves