112704
Formaldehyde-sodium bisulfite adduct
95%
Synonym(s):
Sodium formaldehyde bisulfite
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About This Item
Linear Formula:
HOCH2SO3Na
CAS Number:
Molecular Weight:
134.09
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
95%
form
solid
mp
200 °C (dec.) (lit.)
functional group
hydroxyl
sulfonic acid
SMILES string
O=S(CO)([O-])=O.[Na+]
InChI
1S/CH4O4S.Na/c2-1-6(3,4)5;/h2H,1H2,(H,3,4,5);/q;+1/p-1
InChI key
UOULCEYHQNCFFH-UHFFFAOYSA-M
Related Categories
General description
Formaldehyde-sodium bisulfite adduct is used as a standard in the synthesis of 3-Hydroxypropionaldehyde (3HPA). It can be assayed by HPLC with fluorometric detection in selected foods.
Application
- Triethyl citrate as a non-toxic solvent in pharmaceutical applications: Explored the use of Triethyl citrate in in-situ forming PLGA implants, focusing on its role as a less toxic solvent compared to traditional options. This application demonstrates the importance of Triethyl citrate in developing safer pharmaceutical formulations (Ramos et al., 2024).
- Triethyl citrate in biodegradable polymer research: Examines the influence of Triethyl citrate on the melt spinning and structural properties of poly(lactic acid) fibers. This study highlights its effectiveness as a plasticizer, enhancing the processability and properties of biodegradable polymers, relevant for controlled drug release systems (Gzyra-Jagieła et al., 2024).
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Stephen Wai Cheung Chung et al.
Journal of AOAC International, 91(1), 98-102 (2008-04-02)
A rapid and accurate method for measuring low part-per-million levels of free and reversibly-bound sulfites in selected foods by using high-performance liquid chromatography (HPLC) with fluorometric detection was developed. Sulfites were extracted with sodium tetrachloromercurate solution and determined by HPLC-fluorescence
Hydroxymethylated polysulphone for islet macroencapsulation allows rapid diffusion of insulin but retains PERV.
P Petersen et al.
Transplantation proceedings, 34(1), 194-195 (2002-04-18)
R Aris et al.
The American review of respiratory disease, 141(3), 546-551 (1990-03-01)
Hydroxymethanesulfonate (HMSA), the bisulfite (HSO3-) adduct of formaldehyde (CH2O), is a common constituent of California acid fogs. HMSA, most stable in a fog pH range of 3 to 5, dissociates at 6.6, the pH of the fluid lining human airways.
Yuegang Zuo
Chemosphere, 51(3), 175-179 (2003-02-20)
The determination of the photo-production rate of hydroxyl radical (OH) in atmospheric liquids is of fundamental importance to an understanding of atmospheric aquatic chemistry. Recently, several studies have been performed to examine the photo-chemical formation rate of OH in cloud
J Kawai et al.
Astrobiology, 19(4), 506-516 (2019-01-08)
While formaldehyde (HCHO) was likely generated in Earth's prebiotic atmosphere by ultraviolet light, electrical discharge, and/or volcano-created lightning, HCHO could not have accumulated in substantial amounts in prebiotic environments, including those needed for prebiotic processes that generate nucleosidic carbohydrates. HCHO
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