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SML2637

Sigma-Aldrich

NPD8733

≥98% (HPLC)

Synonym(s):

N-[2-(4-Methoxybenzoyl)-3-benzofuranyl]acetamide

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$164.00
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Estimated to ship on15 April 2025


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5 MG
$164.00
25 MG
$658.00

About This Item

Empirical Formula (Hill Notation):
C18H15NO4
CAS Number:
Molecular Weight:
309.32
UNSPSC Code:
12352200
NACRES:
NA.77

$164.00


Estimated to ship on15 April 2025


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Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

N(c1c2c([o]c1C(=O)c3ccc(cc3)OC)cccc2)C(=O)C

InChI

1S/C18H15NO4/c1-11(20)19-16-14-5-3-4-6-15(14)23-18(16)17(21)12-7-9-13(22-2)10-8-12/h3-10H,1-2H3,(H,19,20)

InChI key

NQZBUYPGHZTWIR-UHFFFAOYSA-N

Biochem/physiol Actions

NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. NPD8733 binds to valosin-containing protein (VCP)/p97.
inhibitor of cancer cell-enhanced fibroblast migration

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Kruthi Suvarna et al.
The Journal of biological chemistry, 294(9), 2988-2996 (2019-01-06)
Carcinoma-associated fibroblasts are fibroblasts activated by surrounding cancer cells. Carcinoma-associated fibroblasts exhibit enhanced cell migration, which plays an important role in cancer metastasis. Previously, we demonstrated enhanced migration of NIH3T3 fibroblasts when they were cultured in the presence of MCF7

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