SML1373

Angiotensin A trifluoroacetate salt

≥98% (HPLC)

• Synonym(s): ARVYIHPF trifluoroacetate salt, Ala-Arg-Val-Tyr-Ile-His-Pro-Phe trifluoroacetate salt, Ang A trifluoroacetate salt
• Empirical Formula (Hill Notation): C₄₉H₇₁N₁₃O₁₀ · xC₂HF₃O₂
• CAS Number: 51833-76-2
• Molecular Weight: 1002.17 (free base basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825825
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• storage temp.: −20°C
• SMILES string: [H]N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@]([C@@H](C)CC)([H])C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)CC3=CN=CN3)=O)=O)CC(C=C4)=CC=C4O)=O)=O)=O)C
• InChI: 1S/C49H71N13O10/c1-6-28(4)40(46(69)58-36(24-32-25-53-26-55-32)47(70)62-21-11-15-38(62)44(67)59-37(48(71)72)23-30-12-8-7-9-13-30)61-43(66)35(22-31-16-18-33(63)19-17-31)57-45(68)39(27(2)3)60-42(65)34(56-41(64)29(5)50)14-10-20-54-49(51)52/h7-9,12-13,16-19,25-29,34-40,63H,6,10-11,14-15,20-24,50H2,1-5H3,(H,53,55)(H,56,64)(H,57,68)(H,58,69)(H,59,67)(H,60,65)(H,61,66)(H,71,72)(H4,51,52,54)/t28-,29-,34-,35-,36-,37-,38-,39-,40-/m0/s1
• InChI key: CHCOFDZSJYMQMX-NOQNJSOHSA-N

Description

Biochem/physiol Actions

Angiotensin A (Ang A) is an endogenous vasoconstrictor octapeptide. It is a derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid. Angiotensin A has similar affinity as Angiotensin II for AT1 and AT2 receptors with Ki values of 1.6 and 2.3 nM at AT1 and AT2 receptors.

Derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid; endogenous vasoconstrictor peptide.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable