SML0395

Ac-EEMQRR-NH2 trifluoroacetate salt

≥95% (HPLC)

• Synonym(s): Acetyl Hexapeptide-3, Acetyl Hexapeptide-8, Acetyl hexapeptide, Hexapeptide 3
• Empirical Formula (Hill Notation): C₃₄H₆₀N₁₄O₁₂S · xC₂HF₃O₂
• CAS Number: 616204-22-9
• Molecular Weight: 888.99 (free base basis)
• MDL number: MFCD22666393
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825391
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥95% (HPLC)
• form: lyophilized solid
• color: white
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: OC(=O)C(F)(F)F.CSCC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(C)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
• InChI: 1S/C34H60N14O12S.C2HF3O2/c1-17(49)43-20(8-11-25(51)52)29(57)47-22(9-12-26(53)54)31(59)48-23(13-16-61-2)32(60)46-21(7-10-24(35)50)30(58)45-19(6-4-15-42-34(39)40)28(56)44-18(27(36)55)5-3-14-41-33(37)38;3-2(4,5)1(6)7/h18-23H,3-16H2,1-2H3,(H2,35,50)(H2,36,55)(H,43,49)(H,44,56)(H,45,58)(H,46,60)(H,47,57)(H,48,59)(H,51,52)(H,53,54)(H4,37,38,41)(H4,39,40,42);(H,6,7)/t18-,19-,20-,21-,22-,23-;/m0./s1
• InChI key: RSZPECDVLFYJCF-PXILYFGCSA-N

Description

Amino Acid Sequence

Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2

Biochem/physiol Actions

Ac-EEMQRR-NH2 is a SNAP25 N-terminal-derived peptide that inhibits the SNARE complex and possibly blocks neuronal exocytosis. Ac-EEMQRR-NH2 exhibits anti-inflammatory and anti-wrinkle activity. It is used as anti-wrinkle cosmetics ingredient.

Ac-EEMQRR-NH2 is an anti-inflammatory and anti-wrinkle peptide.

Ac-EEMQRR-NH2 trifluoroacetate salt is considered 4000 times less toxic than botulin toxin. It has restricted transdermal penetration and hence has limited application for topical usage.[1]

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable